INVESTIGADORES
ANGEL Sergio Oscar
capítulos de libros
Título:
Toxoplasma gondii: without stress there is no life
Autor/es:
FIGUERAS MJ; ANGEL SO; COCERES V; ALOMAR L
Libro:
Stress Response in Microbiology
Editorial:
Caister Academic Press
Referencias:
Año: 2012;
Resumen:
Toxoplasma gondii is an important pathogen of human and domestic animals. It has a complex life cycle which includes the transition from one host to another, being only exposed to environment during one stage, as highly resistant oocysts. Interestingly, in the intermediate host (non-feline mammalians and birds) the parasite presents an asexual cycle with two stages that can interconverse without its passage in the definite host (felines). The asexual cycle is very important in the establishment of the infection and on its pathogenesis and it could be driven by different kind of stressors. Therefore, the response to environmental and host stress is essential to their viability and successful progression through their life cycle. The heat shock proteins are key molecules in the resistance to different stressors but also in the optimal differentiation as well as other biological processes of T. gondii. This chapter summarizes the finding on different aspect of T. gondii stress responses and the implication of these processes in biology and pathogenesis of this parasite.