Ovarian growth impairment after chronic exposure to Roundup Ultramax® in the estuarine crab Neohelice granulata

MEDESANI, DANIEL A.; RODRÍGUEZ, ENRIQUE M.; CANOSA, IVANA S.; SILVEYRA, GABRIELA R.; AVIGLIANO, LUCIANA; AVIGLIANO, LUCIANA; MEDESANI, DANIEL A.; RODRÍGUEZ, ENRIQUE M.; CANOSA, IVANA S.; SILVEYRA, GABRIELA R.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

SPRINGER HEIDELBERG

Año: 2018 vol. 25 p. 1568 - 1575

0944-1344

Adult females of the estuarine crab Neohelice granulata were exposed to the glyphosate formulation Roundup Ultramax® during the entire 3-month pre-reproductive period. At the end of the assay, a significant higher increment of glycemia was noted at both glyphosate concentrations assayed (0.01 and 0.2 mg/L, acid equivalent). Although no differences were observed in the gonadosomatic index, a significantly higher proportion of reabsorbed vitellogenic oocyte was observed at the highest glyphosate concentration, together with a significant decrease of vitellogenin content in the ovary. In addition, some in vitro assays were carried out by co-incubating small pieces of ovary with or without the addition of Roundup; at both concentrations tested (same as those used in vivo), a decrease in the ovarian vitellogenin content was observed, whereas the ovarian protein synthesis was significantly inhibited by glyphosate at 0.2 mg/L in the Roundup formulation used.