GH, IGF-1 and GH receptors mRNA expression in response to growth impairment following a food deprivation period in individually housed cichlid fish Cichlasoma dimerus.

TOMÁS H. DELGADIN; DANIELA I. PÉREZ SIRKIN; MARÍA PAULA DI YORIO; SILVIA EDA ARRANZ; PAULA G. VISSIO

FISH PHYSIOLOGY AND BIOCHEMISTRY

SPRINGER

Lugar: Berlin; Año: 2014 vol. 41 p. 51 - 60

0920-1742

Cichlasoma dimerus is a social cichlid fish capable of growing at high rates under laboratory conditions, but knowledge on somatic growth regulation is still unclear. Growth hormone (GH)/insuline like growth hormone I (IGF-I) axis is the key regulator of somatic growth in vertebrates. Two types of growth hormone receptors have been described in teleost fish, named GH receptor type 1 (GHR1) and type 2 (GHR2). In addition, isoforms of these receptors lacking part of the intracellular region have been described. The aim of this study was to evaluate the somatic growth, liver histology and changes in the GH/IGF-I axis after four weeks of food deprivation in C. dimerus. Four week fasted fish showed reductions in specific growth rates in body weight(p