IIMYC   23581
INSTITUTO DE INVESTIGACIONES MARINAS Y COSTERAS
Unidad Ejecutora - UE
artículos
Título:
Effect of anodized zirconium implants on early osseointegration process in adult rats: a histological and histomorphometric study
Autor/es:
GONZÁLEZ, ARIEL; CERÉ, SILVIA; GONZÁLEZ, ARIEL; CERÉ, SILVIA; KATUNAR, MARÍA ROSA; DÍAZ, ALCIRA OFELIA; KATUNAR, MARÍA ROSA; DÍAZ, ALCIRA OFELIA; TANO DE LA HOZ, MARÍA FLORENCIA; GOMEZ SANCHEZ, ANDREA; TANO DE LA HOZ, MARÍA FLORENCIA; GOMEZ SANCHEZ, ANDREA
Revista:
Progress in Biomaterials
Editorial:
Springer
Referencias:
Año: 2019 vol. 8 p. 249 - 260
ISSN:
2194-0509
Resumen:
Since surface plays a key role in bioactivity, the response of the host to the biomaterial will determine the success or failureof the prosthesis. The purpose of this study is to make an exhaustive analysis of the histological and histochemical characteristicsof new bone tissue around Zr implants anodized at 60 V (Zr60) supported by histomorphometric methods in a ratmodel. Fibrous tissue was observed around the control implants (Zr0) and osteoblasts were identified on the trabeculae closeto the implantation site that showed typical cytological characteristics of active secretory cells, regardless of the surfacecondition. The histomorphometrical analysis revealed a significant increase in cancellous bone volume, trabecular thicknessand in trabecular number together with a decrease in trabecular separation facing Zr60. TRAP staining showed that there wasa relative increase in the number of osteoclasts for Zr60. In addition, a larger number of osteoclast with a greater number ofnuclei were detected in the tibiae for Zr60. This research demonstrated that the new bone microarchitecture in contact withZr60 is able to improve the early stages of the osseointegration process and consequently the primary stability of implantswhich is a crucial factor to reduce recovery time for patients.