Association between inflammatory diet score, obesity and breast cancer in Córdoba, Argentina

BECARIA COQUET, JULIA; CAMISASSO M.; ROMÁN, MARÍA DOLORES; ABALLAY, LAURA R.; CABALLERO V.; NICLIS, CAMILA; MUÑOZ, SONIA E.; GONZÁLEZ MF.; TUMAS, NATALIA; DÍAZ, MARÍA DEL PILAR

Buenos Aires

Congreso; IUNS 21st International Congress of Nutrition; 2017

International Union of Nutritional Sciences

Background and objectives: Breast cancer (BC) is a multifactorialdisease; several environmental factors have been linkedto this pathology. Specifically, obesity and inflammatory diet havebeen associated with an increased risk of BC in women. Endocrinechanges related to these factors trigger an inflammatory response,which favors the occurrence of BC. The aim of this research wasto assess the association between the consumption of an inflammatorydiet and BC risk, taking into account nutritional status, inCórdoba province (Argentina).Methods: A case-control study was conducted during 2008-2016 period (346 cases of BC and 566 controls). An inflammatorydiet score was developed including 15 dietary variables (nutrientsand food groups consumption), obtained through a validatedFFQ. A score (0, 0.5 or 1) was assigned for each variable includedin the score depending on the compliance of dietary recommendations.A higher score indicated a higher degree of adherence toan inflammatory diet. For each woman an inflammatory score wascalculated. A multiple logistic regression model was performed toassess the association between BC occurrence and inflammatorydiet, stratifying by nutritional status.Results: The inflammatory diet score mean was 6.7 (0.9) inall women included in the study. 20% of the women studied wereobese. An increased risk of BC of 42% was observed for each unitof increased in the inflammatory diet score in this group (OddsRatio: 1.42; Confidence Interval: 1.1-1.84).Conclusions: Obese women with an inflammatory diet have agreater risk of BC in Córdoba (Argentina).