Parietin, an anthraquinone derivative isolated from Teleoschistes flavicans, as photosensitizer Type 1

BS KONIGHEIM, LR COMINI, S GRASSO, JJ AGUILAR, J MARIONI, MS CONTIGIANI, SC NúñEZ MONTOYA; SC NÚÑEZ MONTPYA; N JELICICH; GR VERGARA; BS KONIGHEIM, LR COMINI, S GRASSO, JJ AGUILAR, J MARIONI, MS CONTIGIANI, SC NúñEZ MONTOYA; JL CABRERA

Maresias, Sao Paulo

Encuentro; XII LATIN-AMERICAN MEETING ON PHOTOCHEMISTRY AND PHOTOBIOLOGY; 2015

IQSC

For several years, anthraquinone (AQs) derivatives have been thoroughly studied in relation to their photosensitizing properties in photodynamic reactions. Some of them have shown good antibacterial and antiviral effects by means of photosensitization, in where reactive oxygen species (ROS) are increased, such as superoxide anion (O2.¯) (Type I mechanism) and singlet molecular oxygen (1O2) (Type II mechanism), and the subsequent oxidative damage is observed [1]. This time we report the Type I photosensitizing properties of parietin (PTN), an AQ isolated from the lichen species: Teleoschistes flavicans (SW) Norm. (Telochistaceae)[2].