IMBIV 05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Reduction of Candida tropicalis biofilms by the photodynamic action of rubiadin, a natural anthraquinone
Autor/es:
J MARIONI; LR COMINI; JL CABRERA; MG PARAJE; SC NUÑEZ MONTOYA
Lugar:
Maresias, Sao Paulo
Reunión:
Encuentro; XII LATIN-AMERICAN MEETING ON PHOTOCHEMISTRY AND PHOTOBIOLOGY; 2015
Institución organizadora:
IQSC
Resumen:
Enriched-anthraquinones (AQs) extracts of Heterophyllaea pustulata (Rubiaceae), have shown in vitro antifungal effect against Candida biofilms. Purified AQs from bioactive extracts exhibit photosensitizing activity. Antifungal activity of Rubiadin (RUB), a majority AQs from these extracts, was evaluated on Candida tropicalis biofilms, analyzing if this effect could be increased by irradiation and quantifying the reactive oxygen species (ROS) and reactive nitrogen intermediate.
