IMBIV   05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Searching for a methodology to assess in vitro antiviral activity photosensitized
Autor/es:
MUGAS ML; KONIGHEIM BS; AGUILAR JJ; MARIONI J; COMINI LR; CONTIGIANI MS; CABRERA JL; NÚÑEZ MONTOYA SC
Lugar:
Philadelphia
Reunión:
Congreso; GLOBAL PHARM SUMMIT. OMICS INTERNATIONAL; 2015
Institución organizadora:
OMICS INTERNATIONAL
Resumen:
Our research group studies the activity of photosensitizing anthraquinones (AQs), purified from a phototoxic plant, against several viruses. To study the antiviral activity of these AQs (into the infected cells, at some stage of viral replication), which can in turn be photostimulated, an appropriate methodology is needed. Therefore, the aim of this work was to assess two techniques, the Neutral Red uptake assay (NR) and the test of reduction of plaque forming units (PFU), establishing besides the conditions necessary to quantify the in vitro antiviral effect photosensitized.