New hydrogel obtained from a novel dendritic monomer as a promising candidate for biomedical applications

JULIO C. CUGGINO; GERMAN CHARLES; GERARDO GATTI; MIRIAM C. STRUMIA; CECILIA I. ÁLVAREZ IGARZABAL

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Wiley Periodicals, Inc

Lugar: New York; Año: 2013 vol. 101 p. 3372 - 3381

1552-4965

Acid functional hydrogels are a type of materials with many advantages. Over the last years, increasing attention for the synthesis of dendronized polymers has been drawn due to their unique properties of high multivalence in the same surface as compared to conventional polymers. In this study, we report the preparation of novel acid dendronized hydrogels using a dendritic monomer obtained from Behera?s amine. The swelling and rheological performance, the non-toxicity over fibroblast cells and the drug encapsulation capacity of the novel hydrogels suggests that the new materials can achieve great potential as carrier for drug delivery and other potential biomedical applications