Withanolides with Phytotoxic Activity from Two Species of the Genus Salpichroa: S. origanifolia and S. tristis var. lehmannii

VIVIANA E. NICOTRA; ANA V.. BASSO; NATALIA S. RAMACCIOTTI; ROSANA I. MISICO

JOURNAL OF NATURAL PRODUCTS

AMER CHEMICAL SOC

Lugar: Washington; Año: 2013 vol. 76 p. 2219 - 2225

0163-3864

Resumen: Seven new withanolides, salpichrolides OU (17), the known 2,3-dihydrosalpichrolide B (9), a substance not previously isolated from a natural source, as well as three known compounds, including salpichrolide D (8), salpichrolide A (10), and salpichrolide C (11), were isolated and characterized from the aerial parts of Salpichroa origanifolia and S. tristis var. lehmannii. Compounds 14 and 8 have an oxygenated D ring, while compounds 57 and 911 possess a six-membered aromatic D ring. The structures of the isolated compounds were identified by analysis of their spectroscopic data including.Withanolides 1, 3, 8, 10, and 11 exhibited selective radicle growth inhibition toward Lactuca sativa (lettuce) at 150 and 400 ppm.