Development of silver nanoparticles/gelatin thermoresponsive nanocomposites: Characterization and antimicrobial activity

GALDOPÓRPORA, JUAN MANUEL; MORCILLO, MARINA FLORENCIA; IBAR, ANGELINA; PEREZ, CLAUDIO JAVIER; TUTTOLOMONDO, MARIA VICTORIA; DESIMONE, MARTIN FEDERICO

CURRENT PHARMACEUTICAL DESIGN.

BENTHAM SCIENCE PUBL LTD

Año: 2019 vol. 25

1381-6128

Skin and soft tissue infections involve microbial invasion of the skin and underlying soft tissues. To overcome this problem, nanocomposites were obtained using gelatin as a biopolymer scaffold and silver nanoparticles as a wide spectrum antimicrobial agent. Water and glycerol have been used as solvents for the gelatin hydrogel synthesis. This mixture led to a stable and homogeneous biomaterial with improved mechanical properties