INVESTIGADORES
NINAGO mario daniel
congresos y reuniones científicas
Título:
Synthesis and characterization of bentonite/alginate based nanocomposite for drug delivery
Autor/es:
SOLEDAD M. M. LENCINA; MARIO D. NINAGO; ROGELIO DISANTO; ANDRÉS E. CIOLINO; MARCELO A. VILLAR
Lugar:
Buenos Aires
Reunión:
Conferencia; COMAT CONFERENCE 2015; 2015
Institución organizadora:
6th International Conference on Science and Technology of Composite Materials
Resumen:
Hydrogels based on calcium alginate and semi-interpenetrating networks of alginate/poly(N-isopropylacrylamide (ALG/PN) crosslinked by calcium ions and different bentonite (BN) concentration were prepared. The characterization of these composites revealed that hydrogel formation by dropping is an efficient method to entrap PN and BN in alginate beads. Swelling assays were performed at 24 and 37 °C. ALG/PN/BN hydrogels presented a thermos-response associated to PN content, showing lower SR values at 37°C. Furthermore, BN addition into ALG/PN beads produced a significant reduction of SR and this effect is more evident with higher amounts of BN. In contrast, ALG/BN beads SR values increased with temperature due to the higher chain mobility.