CONVERTI, AYELÉN; BIANCHI, MARÍA SILVIA; MARTINEZ, MARIO D.; MONTANER, ALEJANDRO D.; LUX-LANTOS, VICTORIA; BONAVENTURA, MARÍA MARTA

IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation

Physiological Reports; Año: 2023 vol. 11

RUBIONE, JULIA; SBRASCINI, SANDRA M.; MIGUEL, BERNARDO; LEIGUARDA, CANDELARIA; CORONEL, MARÍA F.; MCCARTHY, CARLY J.; MONTANER, ALEJANDRO; VILLAR, MARCELO J.; BRUMOVSKY, PABLO R.

Modulation of the Inflammatory Response by Pre-emptive Administration of IMT504 Reduces Postoperative Pain in Rats and has Opioid-Sparing Effects

JOURNAL OF PAIN; Año: 2023 vol. 24 p. 991 - 1008

CASADEI, MAILÍN; FIORE, ESTEBAN; RUBIONE, JULIA; DOMÍNGUEZ, LUCIANA MARÍA; CORONEL, MARÍA FLORENCIA; LEIGUARDA, CANDELARIA; GARCÍA, MARIANA; MAZZOLINI, GUILLERMO; VILLAR, MARCELO J.; MONTANER, ALEJANDRO; CONSTANDIL, LUIS; ROMERO-SANDOVAL, E. ALFONSO; BRUMOVSKY, PABLO R.

IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injured nerve

PAIN; Lugar: Amsterdam; Año: 2022

LEIGUARDA, C.; VILLARREAL, A.; POTILINSKI, C.; PELISSIER, T.; CORONEL, M.F.; BAYO, J.; RAMOS, A.J.; MONTANER, A.; VILLAR, M.J.; CONSTANDIL, L.; BRUMOVSKY, PABLO R.

Intrathecal Administration of an Anti‐nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization

JOURNAL OF NEUROIMMUNE PHARMACOLOGY; Año: 2021

BIANCHI, STEFANIA; MARTÍNEZ ALLO, VERÓNICA C.; MASSIMINO, MILENA; LAVIGNOLLE HEGUY, MARÍA DEL R.; BORZONE, FRANCISCO R.; GOMEZ BUSTILLO, SOFÍA; CHASSEING, NORMA A.; LIBERTUN, CARLOS; MONTANER, ALEJANDRO D.; RABINOVICH, GABRIEL A.; TOSCANO, MARTA A.; LUX-LANTOS, VICTORIA A.; BIANCHI, MARÍA S.

Oligonucleotide IMT504 Improves Glucose Metabolism and Controls Immune Cell Mediators in Female Diabetic NOD Mice IMT504, a Potential Therapy for Type 1 Diabetes

Nucleic Acid Therapeutics; Lugar: New York; Año: 2021 vol. 31 p. 155 - 171

LEIGUARDA C; POTILINSKI, C; RUBIONE J; TATE P; VILLAR MJ; MONTANER AD; BISAGNO V; CONSTANDIL, L; BRUMOVSKY P

IMT504 provides analgesia by modulating cell infiltrate and inflammatory milieu in rats with hindpaw inflammation

JOURNAL OF NEUROIMMUNE PHARMACOLOGY; Lugar: Berlin; Año: 2020

SIERRA, ROMINA; GÓMEZ BUSTILLO, SOFÍA; KAMENEVA, POLINA; FIORE, ESTEBAN J.; MAZZONE, GRACIELA L.; BORDA, MAXIMILIANO; BLANCO, MARÍA V.; USUARDI, CHIARA; FURLAN, ALESSANDRO; ERNFORS, PATRIK; ALANIZ, LAURA; MONTANER, ALEJANDRO DANIEL; ADAMEYKO, IGOR; AQUINO, JORGE B.

Contribution of neural crest and GLAST+ Wnt1+ bone marrow pericytes with liver fibrogenesis and/or regeneration

LIVER INTERNATIONAL; Lugar: Londres; Año: 2020 vol. 40 p. 977 - 987

LEIGUARDA, CANDELARIA; CORONEL, MARÍA FLORENCIA; MONTANER, ALEJANDRO DANIEL; VILLAR, MARCELO JOSÉ; BRUMOVSKY, PABLO RODOLFO

Long-lasting ameliorating effects of the oligodeoxynucleotide IMT504 on mechanical allodynia and hindpaw edema in rats with chronic hindpaw inflammation

NEUROSCIENCE LETTERS; Año: 2018 vol. 666 p. 17 - 23

ZORZOPULOS J; OPAL MS; HERNANDO INSÚA A; RODRIGUEZ JM; ELÍAS F; FLÓ J; LÓPEZ RA; CHASSEING NA; LUX-LANTOS VA; CORONEL MF; RAUL FRANCO; ELÍAS F; MONTANER AD; DAVID HORN

Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy

World Journal of Stem Cells; Lugar: Pleasanton, CA 94588; Año: 2017 vol. 9 p. 45 - 67

BIANCHI MS; BIANCHI S; HERNANDO-INSÚA A; MARTINEZ L; LAGO N; LIBERTUN C; CHASSEING NA; MONTANER A; LUX-LANTOS V

Proposed mechanisms for oligonucleotide IMT504 induced diabetes reversion in a mouse model of immunodependent diabetes

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Lugar: Bethesda; Año: 2016

JUAN M. RODRIGUEZ; JOSÉ MARCHISIO; MARIELA LÓPEZ; ANDREA ZIBLAT; FERNANDA ELÍAS; JUAN FLÓ; DAVID HORN; JORGE ZORZOPULOS; ALEJANDRO MONTANER

PyNTTTTGT and CpG Immunostimulatory Oligonucleotides: Effect on Granulocyte/Monocyte Colony-Stimulating Factor (GMCSF) Secretion by Human CD56+ (NKand NKT) Cells

PLOS ONE; Lugar: San Francisco; Año: 2015 vol. 10 p. 1 - 20

RAUL FRANCO; JUAN M. RODRIGUEZ; FERNANDA ELIAS; ANDRES HERNANDO-INSUA; JUAN FLO; RICARDO LÓPEZ; CARLOS NAGLE; NESTOR LAGO; JORGE ZORZOPULOS; DAVID HORN; ALEJANDRO D. MONTANER,

Non-Clinical Safety Studies of IMT504, a Unique Non-CpG Oligonucleotide

OLIGONUCLEOTIDES; Lugar: New York; Año: 2014 vol. 24 p. 267 - 282

ALEJANDRO D. MONTANER; ANALIA DE NICHILO; JUAN M. RODRIGUEZ; ANDRÉS HERNANDO INSUA; JUAN FLÓ; RICARDO LÓPEZ; VERÓNICA SIERRA; CLAUDIO PAOLAZZI; OSCAR LARGHI; DAVID HORN; JORGE ZORZOPULOS; FERNANDA ELIAS

IMT504: A New and Potent Adjuvant for Rabies Vaccines Permitting Significant Dose Sparing

World Journal of Vaccines; Año: 2012 p. 182 - 188

BIANCHI MS; CALVO V; CHASSEING NA; LAGO N; LIBERTUN C; MONTANER AD; LUX-LANTOS VA

Oligodeoxynucleotide IMT504: lack of effect on immune parameters during islet regeneration in single dose streptozotocin-induced diabetes

Diabetes Metab Res Rev; Lugar: Hoboken, N.J.; Año: 2012 vol. 28 p. 156 - 163

MONTANER AD; DENICHILO A; RODRÍGUEZ JM; FLÓ J; LÓPEZ RA; PONTORIERO A; SAVY V; BAUMEISTER E; FRANK R; ZORZOPULOS J; ELÍAS F

Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire

Nucleic Acid Therapeutics; Año: 2011 vol. 21 p. 265 - 274

M. S. BIANCHI; A. HERNANDO-INSÚA; N. A. CHASSEING; J. M. RODRÍGUEZ; F. ELÍAS; N. LAGO; J. ZORZOPULOS; C. LIBERTUN; A. D. MONTANER; V. A. LUX-LANTOS

Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers

DIABETOLOGIA; Lugar: Bristol; Año: 2010 vol. 53 p. 1184 - 1189

ANDRÉS HERNANDO-INSÚA; JUAN M. RODRIGUEZ; FERNANDA ELÍAS; JUAN FLÓ; RICARDO LÓPEZ; RAUL FRANCO; NESTOR LAGO; JORGE ZORZOPULOS; ALEJANDRO D. MONTANER

A high dose of IMT504, PyNTTTGT Prototype Immunostimulatory Oligonucleotide, Does Not Alters Embryonic Development in Rats

OLIGONUCLEOTIDES; Lugar: New Rochelle, NY ; Año: 2010 vol. 20 p. 33 - 36

MARIA FLORENCIA CORONEL; ANDRES HERNANDO-INSUA; JUAN MANUEL RODRIGUEZ; FERNANDA ELIAS; NORMA ALEJANDRA CHASSEING; ALEJANDRO DANIEL MONTANER; MARCELO JOSE VILLAR

Oligonucleotide IMT504 reduces neuropathic pain after peripheral nerve injury

NEUROSCIENCE LETTERS; Lugar: Ireland; Año: 2008 vol. 444 p. 69 - 73

ANDRÉS HERNANDO INSÚA,; ALEJANDRO D. MONTANER,; JUAN M. RODRIGUEZ,; FERNANDA ELÍAS,; JUAN FLÓ,; RICARDO A. LÓPEZ,; JORGE ZORZOPULOS,; ERICA L. HOFER; NORMA A. CHASSEING

IMT504, the Prototype of the Immunostimulatory Oligonucleotides of the PyNTTTTGT Class, Increases the Number of Progenitors of Mesenchymal Stem Cells Both In Vitro and In Vivo: Potential Use in Tissue Repair Therapy

STEM CELLS; Lugar: Charlotte, NC; Año: 2007 vol. 25 p. 1047 - 1054

JUAN M. RODRIGUEZ,; FERNANDA ELÍAS,; JUAN FLÓ,; RICARDO A. LÓPEZ,; JORGE ZORZOPULOS,; ALEJANDRO D. MONTANER

Immunostimulatory PyNTTTTGT Oligodeoxynucleotides: Structural Properties and Refinement of the Active Motif

OLIGONUCLEOTIDES; Lugar: New York; Año: 2006 vol. 16 p. 275 - 285

JUAN M. RODRIGUEZ,; FERNANDA ELIAS; ALEJANDRO MONTANER,; JUAN FLO,; RICARDO A. LOPEZ,; JORGE ZORZOPULOS,; RAUL J. FRANCO,; SILVINA P. LENIAL,; MARIELLA LOPEZ SALÓN,; MARIA L. PIRPIGNANI,; JORGE SOLIMANO,; GUY GARAY,; DARDO RIVEROS,; JOSE FERNANDEZ; ROBERTO CACCHIONE,; JUAN DUPONT

OLIGONUCLEOTIDE IMT504 INDUCES AN IMMUNOGENIC PHENOTYPE AND

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 2006 vol. 66 p. 9 - 16

ALEJANDRO D. MONTANER,; ANALIA DE NICHILO,; FERNANDA ELIAS,; JUAN M. RODRIGUEZ,; JUAN M. FLÓ,; RICARDO A. LÓPEZ,; JORGE ZORZOPULOS,; RONALD FRANK

Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route

VACCINE; Año: 2006 vol. 24 p. 1889 - 1896

ELIAS F, FLO J, RODRIGUEZ J, DE NICHILO A, LOPEZ RA, ZORZOPULOS J, NAGLE C, LAHOZ M AND MONTANER A.

PyNTTTTGT Prototype Oligonucleotide IMT504 is a Potent Adjuvant for the Recombinant Hepatitis B Vaccine that Enhances the Th1 Response

VACCINE; Año: 2005 vol. 23 p. 3597 - 3603

FERNANDA ELIAS; JUAN FLO; RICARDO LOPEZ; JORGE ZORZOPULOS; ALEJANDRO MONTANER; JUAN M. RODRUGUEZ

Strong Cytosine-Guanosine-Independent Immunostimulation in Humans and Other Primates by Synthetic Oligodeoxynucleotides with PyNTTTTGT Motifs

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda, MD; Año: 2003 p. 3697 - 3704

MONTANER, ALEJANDRO D.; MONGIAT, LUCAS; LUX-LANTOS, VICTORIA A.; WARBY, CAROL; CHEWPOY, BRAD; BIANCHI, MARÍA S.; LIBERTUN, CARLOS; RIVIER, JEAN E.; SHERWOOD, NANCY M.; SOMOZA, GUSTAVO M.

Guinea pig gonadotropin-releasing hormone: Expression pattern, characterization and biological activity in rodents

NEUROENDOCRINOLOGY; Año: 2002 vol. 75 p. 326 - 338

MONTANER, ALEJANDRO D.; MONGIAT, LUCAS; LUX-LANTOS, VICTORIA A.R.; PARK, MIN KYU; FISCHER, WOLFGANG H.; CRAIG, A. GREY; RIVIER, JEAN E.; LESCHEID, DAVID; LOVEJOY, DAVID; LIBERTUN, CARLOS; SHERWOOD, NANCY M.; SOMOZA, GUSTAVO M.

Structure and biological activity of gonadotropin-releasing hormone isoforms isolated from rat and hamster brains

NEUROENDOCRINOLOGY; Año: 2001 vol. 74 p. 202 - 212

MONTANER, ALEJANDRO D.; PARK, MIN KYU; FISCHER, WOLFGANG H.; CRAIG, ANTHONY G.; CHANG, JOHN P.; SOMOZA, GUSTAVO M.; RIVIER, JEAN E.; SHERWOOD, NANCY M.

Primary Structure of a Novel Gonadotropin-Releasing Hormone in the Brain of a Teleost, Pejerrey 1

ENDOCRINOLOGY; Año: 2001 vol. 142 p. 1453 - 1460

MONTANER, ALEJANDRO D.; GONZALEZ, OLGA; PAZ, DANTE A.; AFFANNI, JORGE M.; SOMOZA, GUSTAVO M.

Gonadotropin-releasing hormone (GnRH) variants in a lizard brain: Is mammalian GnRH being expressed?

GENERAL AND COMPARATIVE ENDOCRINOLOGY; Año: 2000 vol. 119 p. 121 - 131

MONTANER, ALEJANDRO D.; SOMOZA, GUSTAVO M.; KING, JUDY A.; BIANCHINI, JUAN J.; BOLIS, C. GIULIANA; AFFANNI, JORGE M.

Chromatographic and immunological identification of GnRH (Gonadotropin-releasing hormone) variants. Occurrence of mammalian and a salmon-like GnRH in the forebrain of an eutherian mammal: Hydrochaeris hydrochaeris (Mammalia, Rodentia)

REGULATORY PEPTIDES; Año: 1998 vol. 73 p. 197 - 204