INVESTIGADORES
LUCINI Maria magdalena
artículos
Título:
Design Considerations in the sequential analysis of matched case-control data
Autor/es:
M. FAZIL BAKSH; SUSAN TODD; WHITEHEAD JOHN; LUCINI, MARÍA MAGDALENA
Revista:
STATISTICS IN MEDICINE
Editorial:
JOHN WILEY & SONS LTD
Referencias:
Lugar: Londres; Año: 2005 vol. 24 p. 853 - 867
ISSN:
0277-6715
Resumen:
A role for sequential test procedures is emerging in genetic and epidemiological studies using banked biological resources. This stems from the methodology´s potential for improved use of information relative to comparable fixed sample designs. Studies in which cost, time and ethics feature prominently are particularly suited to a sequential approach. In this paper sequential procedures for matched case?control studies with binary data will be investigated and assessed. Design issues such as sample size evaluation and error rates are identified and addressed. The methodology is illustrated and evaluated using both real and simulated data sets.
