Link between the biological clock and diabetes: preliminary studies in Jujuy province.

HERNANDEZ DE BORSETTI N.E

Tucumán

Jornada; XXX Jornadas Científicas, Asociación de Biología de Tucumán; 2013

Sociedad de Biología de Tucumán

LINK BETWEEN THE BIOLOGICAL CLOCK AND DIABETES: PRELIMINARY STUDIES IN JUJUY PROVINCE Reader M.M.1; Guanuco A.1; Baffa-Trasci N.1; Andrade A.J.1; Rios J.J.2; Hernández de Borsetti N.1; Alfaro E.1; Borsetti H.M.1 Laboratorio de Biología Molecular, (InBiAl), Universidad Nacional de Jujuy. Av Bolivia 1661. CP4600. Jujuy. Argentina. 2Consultorio de Atención al Diabético. Argañaráz 285. CP4600. Jujuy. E-mail: hborsetti@yahoo.com.ar Evening chronotype is associated with poor glycemic control in type 2 diabetic (DM2) patients in the northern hemisphere, but no reference was found for Argentina. The aim of this study was to test these findings in a different genetic background. A total of 270 DM2 subjects from Jujuy province, 193 women (24-82 years old) and 97 men (26-79 years old), were screened for diurnal preference (Horne-Östberg questionnaire). Glycated hemoglobin A1c (HbA1c), total cholesterol, HDL, LDL and triglycerides values were obtained from medical records collected during a 1-5 year period depending on the patient. ANOVA was performed and mean test (Scott & Knott, Tukey‟s and LSD) for a significance level of p