Simple and ecofriendly synthesis of dihydropyrimidinones (thiones), dihydropyridines, and pyridines using 3-formylchromones as substrates assisted by a recyclable Preyssler heteropolyacid

SANCHEZ, LAURA M.; PASQUALE, GUSTAVO; SATHICQ, ÁNGEL; RUIZ, DIEGO; JIOS, JORGE; FERREIRA DE SOUZA, ANDREA L.; ROMANELLI, GUSTAVO P.

HETEROATOM CHEMISTRY

JOHN WILEY & SONS INC

Año: 2016 vol. 27 p. 295 - 305

1042-7163

Several dihydropyrimidinones/thiones, 1,4-dihydropyridines, and pyridine derivatives were prepared in very good yields and purity values. The corresponding reactions were carried out by employing a bulk Preyssler heteropolyacid H14[NaP5W29MoO110] as an efficient and recyclable catalyst. The preparation of pyridine derivatives was carried out not through a usual procedure, i.e., the opening of the γ-pyrone ring of 3-formylchromone. In general, reactions took place in solvent-free conditions at 80°C during short reaction times.