INVESTIGADORES
MALDONADO GALDEANO Maria Carolina
capítulos de libros
Título:
Probiotics and funtional foods in Immunosupressed host
Autor/es:
NOVOTNY NUÑEZ, IVANNA; PALOMAR, MARTÍN; DE MORENO DE LEBLANC, ALEJANDRA; MALDONADO GALDEANO, CAROLINA; PERDIGÓN, GABRIELA.
Libro:
Biotechnology of Lactic Acid Bacteria. Novel Applications
Editorial:
Wiley Blackwell
Referencias:
Año: 2016; p. 134 - 143
Resumen:
The intestine is colonized by several bacterial species comprising the normal microbiota.It is known that exist an active dialogue between the commensal microorganisms and the intestinal epithelial and immune cells. This cross talk can produce different responses of the gut immune system in order to maintain the homeostasis.Daily enter with food different microorganisms that can influence this balance both positively and negatively. Among the beneficial microorganisms we can mention those that are contained in fermented products called probiotics One of the main properties attributed to the probiotics is the improvement of the host immune states. It was demonstrated that probiotic fermented milk administration activated mainly the innate immune response, and promoted immunity at sites outside the gut such as bronchus and mammary glands.Experimental animal models are useful to understand the mechanisms implicated in the probiotic interaction with the intestinal epithelial and the immune cells. In this sense we used different experimental models where the activation of the immune system is compromised, such as malnutrition (obesity and malnutrition) and stress process.The stimulation of the intestinal and systemic immune response affected by malnutrition or stress was restored when a probiotic bacteria or a probiotic fermented milk was administered.