PERSONAL DE APOYO
CABRERA fernanda Anabel
artículos
Título:
A comparative study of spray-dried medicinalplant aqueous extracts. Drying performance andproduct quality.
Autor/es:
BUCALÁ V.; PIÑA J.; RAMÍREZ RIGO M.V.; GALLO L.; CABRERA F.
Revista:
CHEMICAL ENGINEERING RESEARCH & DESIGN
Editorial:
INST CHEMICAL ENGINEERS
Referencias:
Año: 2015 p. 681 - 694
ISSN:
0263-8762
Resumen:
Aclaración: En esta publicación participe como colaboradora, asistiendoen el uso de equipos y puesta a punto de técnicas de caracterización. Estoy incluida en los agradecimientos (The authors thank Lic. F. Cabrera (PLAPIQUI) for her technical assistance.)In the manufacture of herbal medicinal tablets, dried plant extracts are employed as thetherapeutic ingredient. These powders, usually obtained by spray drying, are typically hygro-scopic and possess poor flow and compactability for the manufacture of tablets by directcompression (DC). Besides, spray-drying operating conditions and liquid feed compositionare reported to be dependent on the herbal medicine. Consequently, the production of driedextracts implies long new product development times. Therefore, the goal of this paper wasto: (a) provide recommendations as initial production point of herbal powders suitable forDC by spray drying and (b) study the powder properties to identify those that are affectedby the extract nature. Particularly, a unique set of operating conditions was found to beappropriate to produce powders of seven different medicinal plant extracts. In fact, all thespray-dried products showed adequate flowability, stability and compactability.Powders properties, as particle size and morphology, moisture content, hygroscopicity,flowability and compact hardness were not a function of the type of herb. Conversely, theprocess yield and glass transition temperature, particle and bulk densities, powder compo-sition, compact porosity, wetting and disintegration times were found to be dependent onthe chemical nature of the herbs.