CONICET | Buscador de Institutos y Recursos Humanos

Many cancer patients have received chemotherapeutic agents during the course of illness, treatment based on cell destruction potential by growth interruption. Within this group, plants have been thoroughly used in the treatment of these maligned diseases. Many drugs have been extracted from plants. It is worth to mention as example the use of vinblastine, vincristine, podophyllotoxin, taxol. The latter is a potent anticancer agent, which was extracted from species of the genus Taxus, constituting the most used antineoplastic agent at the present time. These drugs that at the moment are part of international pharmacopeia products, arose out of screenings of the National Institute of Cancer (USA) and diverse pharmaceutical laboratories, e.g., Lilly and Bristol-Myers Squibb. The antecedents of ethnobotanical studies demonstrate that several plant genera, belonging to the central region of Argentina, can be selected according to their use in traditional medicine as source of new oncological drugs. The hypothesis of work is that extracts with anticancer capacity can be found, and after chemical studies, new drugs can be obtained. Any plant species can be essentially subjected to a screening, e.g., an anticancer in vitro screening, and furthermore the species of the central region of Argentina, few of which have been subjected to this type of analysis. Aims: Medicinal plants of the central region of Argentina used in domestic medicine were studied by an in vitro test, which allowed to select quickly those extracts that inhibited tumor cell proliferation. Taxus, constituting the most used antineoplastic agent at the present time. These drugs that at the moment are part of international pharmacopeia products, arose out of screenings of the National Institute of Cancer (USA) and diverse pharmaceutical laboratories, e.g., Lilly and Bristol-Myers Squibb. The antecedents of ethnobotanical studies demonstrate that several plant genera, belonging to the central region of Argentina, can be selected according to their use in traditional medicine as source of new oncological drugs. The hypothesis of work is that extracts with anticancer capacity can be found, and after chemical studies, new drugs can be obtained. Any plant species can be essentially subjected to a screening, e.g., an anticancer in vitro screening, and furthermore the species of the central region of Argentina, few of which have been subjected to this type of analysis. Aims: Medicinal plants of the central region of Argentina used in domestic medicine were studied by an in vitro test, which allowed to select quickly those extracts that inhibited tumor cell proliferation. e.g., an anticancer in vitro screening, and furthermore the species of the central region of Argentina, few of which have been subjected to this type of analysis. Aims: Medicinal plants of the central region of Argentina used in domestic medicine were studied by an in vitro test, which allowed to select quickly those extracts that inhibited tumor cell proliferation. in vitro test, which allowed to select quickly those extracts that inhibited tumor cell proliferation.

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