INVESTIGADORES
ALFARO GOMEZ emma laura
congresos y reuniones científicas
Título:
Comparison of head circumference of newborns from Jujuy (Argentina) with the INTERGROWTH-21st Size at Birth Standard
Autor/es:
MARTINEZ, JI; ALFARO, EL; GRANDI, C; DIPIERRI, JE
Lugar:
Encarnación
Reunión:
Congreso; LIV Reunión Anual Sociedad Latinoamericana de Investigación Pediátrica; 2016
Institución organizadora:
Sociedad Latinoamericana de Investigación Pediátrica
Resumen:
Introduction: The increased rate since mid-2015 of microcephaly cases associated with Zika virus in Brazil has determined that WHO declares that this epidemic is an international public health emergency (PHEIC). An emerging problem is the anthropometric diagnosis of microcephaly. It requires deeper knowledge about the cutoffs and references and / or standards to measure the head circumference (HC) and diagnose suspected cases of microcephaly.Objetive: the aim of this study was to compare the distribution of HC by sex and gestational age (GA) of the newborn population of the province of Jujuy, Argentina, with the recently introduced into clinical practice Intergrowth-21st standards. Material and methods: The data source was the Perinatal Informatics System (SIP,PHAO/WHO) in the province of Jujuy (2008-2013). Inclusion criteria were GA between 24 and 42 weeks and birth weight more than 500 grams. Exclusion criteria were major and minor malformations, toxoplasmosis and stillbirth. The mean and SD of HC was calculated by gestational age and sex. The differences with the Intergrowth-21st standard were calculated with the Student t test.Results: The sample was constituted by 46146 newborns (22799 girls and 23347 boys). Newborns from Jujuy presented in both sexes a higher HC compared with the Intergrowth-21st standard on all GA, with statistically significant differences in almost all except 24th, 25th, 27th, 28th and 29th weeks in girls and in the 25th week in boys. Conclusion: The application of Intergrowth-21st standard to Jujuy population may overestimate the suspected cases of microcephaly. New epidemiological studies to assess the specificity and sensitivity of other selection criteria, standards and / or references applicable to the detection of suspected cases of microcephaly are required, such as the recently published recommendations of the WHO (WHO / ZIKV / MOC / 16.3 / Rev3).