Invasive pulmonary aspergillosis and candidiasis in a critically ill patient with COVID-19

BENEDETTI, MARÍA FERNANDA; DE ABREU, MARIELA SOLEDAD; CADENA, ROBERTO CORELLA; ARIAS, MARÍA CONSTANZA; POSSE, GLADYS; CAPECE, PAULA; NUSBLAT, ALEJANDRO; CUESTAS, MARÍA LUJÁN

JOURNAL DE MYCOLOGIE MEDICALE

MASSON EDITEUR

Año: 2022 vol. 32

1156-5233

To the editor,—Invasive fungal superinfections have been increasingly reported in critically ill patients with coronavirus disease-2019(COVID-2019) due to the severe immunomodulation and lymphocytedepletion caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent administration of drugs thattarget the immune system such as corticosteroids [1]. Among them,pulmonary aspergillosis and invasive candidiasis or candidemia havebeen widely reported [2−9].We herein describe one of the first cases in Argentina of combinedprobable pulmonary aspergillosis and candidemia in a previouslyimmunocompetent, critically ill patient with severe COVID-19 pneumonia.