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EFFECT OF DIETARY INTERVENTION WITH CHIA SEED AND CHIA OIL ON VASCULAR FUNCTION AND CARBOHYDRATE METABOLISM
MEDINA ANALIA; ROCO JULIETA; ALARCON GABRIELA; VALOY AGOSTINA; SIERRA LILIANA; JEREZ SUSANA; MEDINA MIRTA
San Miguel de Tucuman
Jornada; XXXVIII Jornadas Científicas - Asociación Biología de Tucumán; 2021
Asociación de Biología de Tucumán
Previously, we have demonstrated the beneficial effects of a functional food enriched with 10% chia oil, equivalent to 4.8 g/day of alpha- linolenic acid (ALA) on vascular function. However, this "%" of oil generated glucose intolerance. The objective of this work was to evaluate whether chia seed supplementation, in a proportion equivalent to 10% of the oil in ALA content, has beneficial effects on vascular function without altering glucose metabolism. 18 male rabbits were divided into 3 groups, fed on a control diet (CD), fed on CD supplemented with 10% chia oil (CD-ACh), and fed on CD supplemented with 224.10 g of chia seed (CD-SCh). After 6 weeks, they were sacrificed and biochemical, clinical, and vascular function parameters were determined. No changes were observed in plasma lipids, weight, blood pressure or abdominal-visceral fat between the treated and CD groups. CD-SCh did not improve the glucose tolerance test relative to CD-ACh. The percentage of relaxation to acetylcholine decreased in CD-SCh with respect to CD-ACh and CD. Treatment with chia seed or chia oil significantly decreased the contractile response to angiotensin II with respect to CD. The contractile response to norepinephrine was significantly decreased in CD-ACh compared to CD-SCh and CD. We conclude that although both chia oil and chia seed have some beneficial effects on vascular function, it is important to take into account the daily intake, since an excess could generate alterations in glucose metabolism.