PERSONAL DE APOYO
FASCIO Mirta Liliana
artículos
Título:
Synthesis of Novel Carbohydrate Acridinone Derivatives with Potential Biological Activities using 1,3-Dipolar Cycloaddition
Autor/es:
MIRTA L. FASCIO; NORMA B. D´ACCORSO; ROLANDO F. PELLÓN; MAITE L. DOCAMPO
Revista:
SYNTHETIC COMMUNICATIONS
Editorial:
Taylor & Francis
Referencias:
Lugar: Londres; Año: 2007 vol. 37 p. 4209 - 4217
ISSN:
0039-7911
Resumen:
Novel 10-{[3-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-4,5-dihydro-5-isoxazolyl]methyl}-9(10H)-acridinone derivatives (13–16) were synthesized by 1,3-dipolar cycloaddition using the carbohydrate derivative as dipole and different 10-allyl-9(10H)-acridinone derivatives (9–12) as dipolarophiles. The new cycloadducts as well as the dipolarophiles precursors were characterized spectroscopically