PERSONAL DE APOYO
FASCIO Mirta Liliana
artículos
Título:
Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocycles derivatives
Autor/es:
CECILIA M. SCORZO; MIRTA L. FASCIO; NORMA B. D´ACCORSO; MARGARITA GUTIÉRREZ CABRERA; LUIS ASTUDILLO SAAVEDRA
Revista:
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
Editorial:
SOC BRASILEIRA QUIMICA
Referencias:
Año: 2010 vol. 21 p. 43 - 48
ISSN:
0103-5053
Resumen:
 We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme.