BECAS
EZQUERRA RIEGA Sergio Dario
artículos
Título:
Chalcogen bearing tetrasubstituted zinc (II) phthalocyanines for CT26 colon carcinoma cells photodynamic therapy
Autor/es:
EZQUERRA RIEGA, SERGIO D.; VALLI, FEDERICO; RODRÍGUEZ, HERNÁN B.; MARINO, JULIETA; ROGUIN, LEONOR P.; LANTAÑO, BEATRIZ; GARCÍA VIOR, MARÍA C.
Revista:
DYES AND PIGMENTS
Editorial:
ELSEVIER SCI LTD
Referencias:
Año: 2022
ISSN:
0143-7208
Resumen:
The synthesis and photochemical properties of six new lipophilic chalcogen tetrasubstituted zinc (II) phthalocyanines and their corresponding water-soluble cationic derivatives were investigated for CT26 colon carcinoma cells photodynamic therapy. Sulfur and selenium phthalocyanines Q-bands are red shifted around 10 nm with respect to the Q-band of oxygen phthalocyanines. The introduction of Se atoms in peripheral position generates non-significant shifts in the absorption spectrum compared to S-bearing phthalocyanine. In addition, Q-band absorption coefficient of selenium phthalocyanines showed to be higher than their respective sulfur and oxygen analogs, which is relevant for dosing in PDT studies. The fluorescence emission maximum wavelength showed the same trend regards to the presence of chalcogen atoms, O
