evolution of canine parvovirus in Argentina between years 2003 and 2010:CPV2c has become the predominant variant the domestic dog population

MARINA GALLO CALDERÓN; CARINA ROMANUTTI; ALEJANDRA D ANTUONO; LETICIA KELLER; NORA MATTION; JOSÉ LA TORRE

VIRUS RESEARCH

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2011

0168-1702

The current frequency of Canine Parvovirus variants (CPV2a, CPV2b and CPV2c) in the Argentine dogpopulation was investigated by PCR amplification of a 583 bp fragment in the VP2 gene. From a total of79 rectal swab samples that have been submitted to our laboratory since 2008, 55 (69.6%) resulted positiveand were further analyzed by direct DNA sequencing. Fifty positives samples (91%) were characterizedas CPV2c variant, which appeared in Argentina in the year 2003 and has been the prevalent type since2008, whereas CPV2a and CPV2b, still found in Argentine dogs, were represented in 3.6% and 5.4% ofthe population, respectively. Considering that CPV2c is spreading worldwide, and that this variant isalso affecting vaccinated dogs, efforts should be made towards the development of new matched CPVvaccines.