INVESTIGADORES
REPETTO Evangelina
artículos
Título:
Two Straightforward Strategies for the Synthesis of Thiodisaccharides with a
Autor/es:
EVANGELINA REPETTO; CARLA MARINO; M. LAURA UHRIG; OSCAR VARELA
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Año: 2008 vol. 2008 p. 540 - 547
ISSN:
1434-193X
Resumen:
Thiodisaccharides having a 1-thiopentofuranose nonreducing end were synthesized by two routes starting from per-Oacylaldofuranoses with arabino, ribo, and xylo configurations. These glycosyl donors were converted into S-glycosyl isothiourea derivatives as precursors of 1-thiofuranose units, which were generated in situ and trapped by a sugar enone to produce, by Michael addition, the thioglycosidic linkage.