INVESTIGADORES
D`ALESSIO Luciana
congresos y reuniones científicas
Título:
Depression in Refractory Temporal Lobe Epileptic Patients
Autor/es:
PAPPAYANNIS C, D`ALESSIO L, GIAGANTE B, IBARRA V, ODDO S, SOLIS P, SALGADO P,
Lugar:
San Diego
Reunión:
Congreso; American Congress of Epilepsy; 2007
Institución organizadora:
American Epilepsy Society
Resumen:
  Depression in Refractory Temporal Lobe Epileptic Patients   Introduction: Depression is the most frequent psychiatric comorbidity in patients with epilepsy. Epidemiological studies indicate that 10-20 % of the patients with controlled epilepsy and 20-60% with recurrent seizures have a depressive disorder.     Objective: The aim of this study was to analyse clinical, electrical and imaging features in refractory temporal lobe epilepsy (RTLE) patients with or without comorbid depression.   Methods We selected a sample of 33 patients with RTLE and depression comorbidity, and they were compared with 27 RTLE patients without any psychiatric disorders in DSM IV. Psychiatric assessment was performed using SCID I of DSM IV. All 60 RTLE patients were evaluated with Video- EEG monitoring and MRI, and were candidates to epilepsy surgery. Sex, age, age of epilepsy onset and epilepsy time duration, febrile convulsions, generalized seizures, status history, presence of unilateral and bilateral hippocampal sclerosis or other structural lesions, and laterality of epileptic discharges diagnosed by video-eeg were determined.  Student t Test and Chi Square were determined.   Results Female gender and the presence of more extended lesions than hippocampal sclerosis (hippocampal sclerosis plus, dual pathology and malformation of cortical development) were more frequent in the group with depression (p<0.05).