Psychiatric disorders in patients with psychogenic non-epileptic seizures, with and without comorbid epilepsy

D`ALESSIO LUCIANA, GIAGANTE BRENDA, ODDO SILVIA, SILVA WALTER, SOLÍS PATRICIA, CONSALVO DAMIAN, KOCHEN SILVIA.

SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION.

Elsevier

Lugar: The Netherlands; Año: 2006 vol. 15 p. 333 - 339

1059-1311

Purpouse: The aim of this study is to describe similarities and differences in epidemiological, psychiatric and semiologic variables between patients with psychogenic none epileptic seizures (PNES) and comorbid epilepsy, (mixed PNES), and patients with PNES without comorbid epilepsy, (pure PNES) Results: Forty three patients with PNES diagnosed by Video-EEG were included. 24 had pure PNES, and 19 mixed PNES. Female population, age, duration of PNES, psychiatric institutionalization, psychopharmacotherapy, dissociative disorders and PTSD (posttraumatic stress disorder), were significantly higher in the pure PNES patients. Suicide attempts, antiepileptic therapy, conversive, affective and personality disorders were frequent in both groups. In the analysis of seizure semiology, the total lack of responsiveness was significantly higher in the mixed PNES group. Conclusions: Pure PNES patients showed similarities and differences in the psychiatric profile, with a greater prevalence of dissociative disorders and PTSD, factors related to psychiatric severity.    Keywords: psychogenic nonepileptic seizures, conversion, dissociation, posttraumatic stress disorder, psychiatric institutionalization, psychopharmacotherapy.