congresos y reuniones científicas
Effect of ACTH on the preovulatory period in cattle and its influence on the expresion of TGFB and its receptors in the ovary.
PEUST, CARLA; BARALE J.; BELOTTI, M.; ORTEGA, H.H.; SALVETTI N.; HEIN G.; MATILLER V.
Mar del Plata
Congreso; LXIII Reunión Anual de la Sociedad Argentina de Investigación Clínica(SAIC)-LXVI Reunión Anual de la Sociedad Argentina de Inmunología (SAI). Reunión anual de la Sociedad Argentina de Fisiología. Sociedad Argentina de Virología (SAV). Reunión Asociación; 2018
The components of the transforming growth factor-beta (TGFB) superfamily exert functions related to follicular development, ovulation and corpus luteum formation. We found an altered expression of these components in the ovaries of animals with cystic ovarian disease (COD). In addition, dairy cattle are exposed daily to stressors that can affect reproductive function. Therefore, the aim of this study was to determine the protein expression of the TGFB isoforms (TGFB1, 2, 3) and its receptors (TGFBR1, 2, 3) by immunohistochemistry in different follicular categories in granulosa and theca interna cells from the ovaries during the preovulatory period of cattle. Animals were treated with adrenocorticotropic hormone (ACTH) every 12 hours for five days before the ovulation. We detected a higher expression of TGFB1 in granulosa cells of large preantral follicles of the ACTH-treated group compared to those of the control group. TGFB2 and TGFB3 showed a higher expression in theca cells of dominant follicles of the ACTH-treated group compared to antral follicles of control group (p