INVESTIGADORES
PEREZ LLORET Santiago
artículos
Título:
Olfactory Dysfunction Evaluation Is Not Affected by Comorbid Depression in Parkinson's Disease.
Autor/es:
MALCO ROSSI; SANTIAGO PÉREZ LLORET; PATRICIO MILLAR VERNETTI; LUCAS DRUCAROFF; E CONSTANZO; DIEGO BALLESTEROS; ANDREA BRIL; DANIEL CERQUETTI; SALVADOR GUINJOAN; MARCELO MERELLO
Revista:
MOVEMENT DISORDERS
Editorial:
WILEY-LISS, DIV JOHN WILEY & SONS INC
Referencias:
Lugar: New York; Año: 2015
ISSN:
0885-3185
Resumen:
BACKGROUND: Olfactory function assessment is an important screening tool for Parkinson´s disease (PD) diagnosis. It is debated whether olfaction is affected by comorbid depression. We assessed the relationship between depression and olfaction in PD and determined whether depression may limit the usefulness of olfactory testing for PD diagnosis.METHODS: Olfaction was evaluated using the Sniffin´ Sticks test and the Hyposmia Rating Scale in four groups of subjects: PD patients without depression (n = 30); PD patients with major depression (PDD; n = 30); major depressive disorder (MDD) patients (n = 29); and healthy controls (HCs; n = 30).RESULTS: No differences were found between PD and PDD patients for total Sniffin´ Sticks test, threshold, discrimination or identification scores, or in Hyposmia Rating Scale, although both groups differed from HCs and MDD patients (P < 0.05), which, in turn, showed similar olfactory scores.CONCLUSIONS: Lack of differences in olfactory impairment between PD and PDD suggest that depression may not contribute to olfactory dysfunction in PD.