GC/MS Analyses of Thiosemicarbazones Synthesized from Acetophenones: Thermal Decay and Mass Spectra Features

BELÉN GASTACA; GASTÓN GALLETTI; HERNÁN RUBÉN SÁNCHEZ; REINALDO PIS DIEZ; MARÍA DE LAS MERCEDES SCHIAVONI; JORGE JAVIER PEDRO FURLONG

International Journal of Analytical Mass Spectrometry and Chromatography

Scientific Research Publishing

Año: 2015 vol. 3 p. 1 - 12

The mass spectral fragmentation of thiosemicarbazones synthesized from acetophenones has been studied by CG/MS. These carbonyl compounds exhibit chromatographic peaks which are not observed in aliphatic analogues or those synthesized from aldehydes. The analysis of the corresponding spectra has allowed structural assignment to the dimerization of gas phase neutral fragments. Theoretical calculations (DFT level) also provide evidence to support the experimental observations.