INVESTIGADORES
DELFINO Cecilia Maria
artículos
Título:
Predominance of Human Lymphotropic T Cell Virus Type 2 Subtype b in Urban Populations of Argentina
Autor/es:
CAROLINA A. BERINI, MARIA E. EIRIN, CECILIA M. DELFINO, MERCEDES WEISSENBACHER, AND MIRNA M. BIGLIONE
Revista:
AIDS RESEARCH AND HUMAN RETROVIRUSES
Editorial:
MARY ANN LIEBERT INC
Referencias:
Lugar: New York; Año: 2012
ISSN:
0889-2229
Resumen:
Human T-lymphotropic virus subtype b (HTLV-2b) infection has been described among aborigines from Northern Argentina, while HTLV-2a has been described in an injecting drug user (IDU) from a Central region, similar to the situation in Spain, the United States, and Brazil. In this study, 22 of the 26 strains analyzed from blood donors and HIV-1+ individuals were HTLV-2b (84.6%) clustering with Amerindian references, while 4 HIV-1+ (15.4%) were HTLV-2a. HTLV-2a sequences were closely related to Brazilian references in contrast to the previous ArgentineanIDU strain that clustered with Africans and Amerindians from North America. In summary, these findings show that HTLV-2b is the major strain circulating in an urban population of Argentina. HTLV-2a/b could have been introduced from endemic South American countries such as Brazil  and because of contact with other populations such as IDUs from Europe despite its introduction due to the increasing internal migration of aborigines to large urban centers. Considering this results and recent data about the dissemination of HTLV-1 in residents of Buenos Aires city, new studies among non-at-risk groups for HTLV-1/2 infection should be performed.