INVESTIGADORES
VIOLA Ivana Lorena
congresos y reuniones científicas
Título:
Redox regulation of the TCP transcription factor TCP15 during high light intensity
Autor/es:
IVANA VIOLA; ALEJANDRA CAMOIRANO; DANIEL GONZALEZ
Reunión:
Congreso; 11th International Congress of Plant Molecular Biology.; 2015
Resumen:
AtTCP15 is a transcription factor from Arabidopsis thaliana that belongs to the TCP family. Proteins of this family are unique to plants and are involved in the regulation of various processes related to plant growth and development, both through control of cell growth and proliferation as modulation of the signaling pathways of hormones and circadian rhythm, thus adjusting cellular metabolism to the demands of internal growth and the received environmental signals.These proteins are named TCP due to the presence of a highly conserved domain that has the ability to bind specific DNA sequences and perform protein-protein interactions. In addition, these proteins are divided into two classes, I and II. Through alignment of TCP protein domains from different species we have found that most TCP class I proteins have a highly conserved cysteine residue. Through experiments of directed mutagenesis we found that the presence of this residue leads to a redox sensitivity that affects the activity of class I proteins TCP in vitro and in vivo. This suggests that changes in the redox state would influence the activity of class I proteins TCP inside the plant and place them as potential mediators of the effect of redox conditions on different aspects of plant development. In this work we describe experiments that allow us to postulate that, in the case of AtTCP15, this modulation of protein activity by the cellular redox state allows to adjust the accumulation of anthocyanin during exposure to high light intensity.