Facile synthesis of methyl alpha- and beta-D-[6-(3)H]galactofuranosides from D-galacturonic acid. Substrates for the detection of galactofuranosidases.

BORDONI, A; LIMA, CARLOS; MARIÑO, K; MUCHNIK DE LEDERKREMER, R; MARINO, CARLA

CARBOHYDRATE RESEARCH

Elsevier

Lugar: Amsterdam; Año: 2008 vol. 343 p. 1863 - 1868

0008-6215

Abstract—Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.