INVESTIGADORES
ZAMPINI Renato
artículos
Título:
Effect of mating on mRNA and protein expression of beta nerve growth factor and its receptor, TrKA, in the oviduct of llama ( Lama glama )
Autor/es:
SARI, LUCIANA M.; ZAMPINI, RENATO; ARGA√ĎARAZ, MARTIN E.; RATTO, MARCELO H.; APICHELA, SILVANA A.
Revista:
MOLECULAR REPRODUCTION AND DEVELOPMENT
Editorial:
WILEY-LISS, DIV JOHN WILEY & SONS INC
Referencias:
Año: 2020
ISSN:
1040-452X
Resumen:
Copulation produces different stimuli in the female reproductive tract in camelids, which lead to ovulation. Expression of β‐nerve growth factor (β‐NGF) and its specific receptor, tropomyosin receptor kinase A (TrKA), was studied comparing the oviductal microenvironment of mated and nonmated llamas. β‐NGF and TrKA were expressed in the llama ampulla, isthmus, and utero‐tubal‐junction (UTJ), and they were mainly colocalized in the apical region of the oviductal mucosa. A TrKA immunosignal was also found in muscle cells and blood vessels, with the highest mark in UTJ muscle cells of copulated females. Both β‐NGF and TrKA transcripts were expressed in the three oviductal segments. Relative TrKA abundance did not differ between mated and nonmated females, but relative β‐NGF abundance was higher in the UTJ of copulated females (p