INVESTIGADORES
KAMENETZKY Laura
artículos
Título:
Several strains of Echinococcus granulosus infect livestock and humans in Argentina
Autor/es:
KAMENETZKY L.; GUTIERREZ A. M.; CANOVA S. G.; HAAG K. L.; GUARNERA E. A.; PARRA A.; GARCIA G. E.; ROSENZVIT M. C.
Revista:
Infection, Genetics and Evolution
Editorial:
Elsevier
Referencias:
Año: 2002 vol. 2 p. 129 - 136
ISSN:
1567-1348
Resumen:
Mitochondrial cytochrome oxidase subunit 1 (CO1) sequencing, Southern blot of a repetitiveDNAelement and single strand conformationpolymorphism of the 5´ non-transcribed region of the cytosolic malate dehydrogenase (MDH) gene were used to determine the extent anddistribution of Echinococcus granulosus genetic variation in Argentina. Five distinct strains of E. granulosus were shown to exist in thecountry. The common sheep, Tasmanian sheep, cattle and camel strains were identified in humans. Unlike the situation found in othercountries, where the common sheep strain is the major source of human contamination, the Tasmanian sheep and camel strains produceda significant number of human infections in some regions of Argentina. This is the first report of cattle strain in humans in South America.Goats could be the natural intermediate host of the camel strain, which was not identified in humans from other regions so far. More thanone genotype was identified in the same geographic area. These findings may have important consequences for human health and thecontrol of hydatid disease. Within-strain differences were also observed, showing the potential of variation of E. granulosus.