INVESTIGADORES
PAROLIN Maria Laura
artículos
Título:
Uniparental origins of the admixed Argentinian Patagonia
Autor/es:
TAMBURRINI C, DE SAINT PIERRE M, BRAVI CM, JURADO MEDINA L, BAILLIET G, VELÁZQUEZ IF, BASSO NG, REAL LE, HOLLEY A, TEDESCHI CM, PAROLIN ML
Revista:
AMERICAN JOURNAL OF HUMAN BIOLOGY
Editorial:
WILEY-LISS, DIV JOHN WILEY & SONS INC
Referencias:
Lugar: New York; Año: 2021
ISSN:
1042-0533
Resumen:
AbstractObjectives: We aimed to contribute to the understanding of the ancient geographic origins of the uniparentally inherited markers in modern admixedArgentinian populations from central Patagonia with new information provided for the city of Trelew. We attempted to highlight the importance of combining different genetic markers when studying population history.Methods: The mtDNA control region sequence was typified in 89 individualsand 12 Y-STR and 15 Y-SNP loci were analyzed in 66 males. With these data,analysis of molecular variance and Network analyses were carried out. Weexhaustively compared the modern data with ancient mtDNA information.Finally, we tested the differences in continental origins estimated by uniparental and previously published biparental markers.Results: Native American mtDNAs (53.9%) increased when maternal ancestorswere born in the northern (81.8%) and southern (58.5%) regions of Argentina orin Chile (77.8%). Population substructure was only observed for Y-chromosomehaplotypes. Some mtDNA haplogroups have been present in the area for at leastca. 2762?2430 and ca. 500 (D1g and D1g4 haplogroups) and ca. 6736 andca. 6620 (C1b and C1c haplogroups) years, respectively. In contrast, haplogroupsB2i2 and C1b13, frequent in modern Patagonia populations, had not been foundin previous ancient DNA studies of the region.Conclusions: The results suggest that Native American ancestry is well preservedin the region. Trelew samples had characteristic native mtDNA haplogroups previously described in Chilean and Argentine Patagonian populations, but notobserved in ancient samples until now. These findings support the idea that theselineages have a recent regional origin. Finally, the estimated proportions of continental ancestry depend on the genetic marker analyzed.