Spatial spread of dengue in a non-endemic tropical city in northern Argentina

JOSÉ F. GIL, MAXIMILIANO PALACIOS, ALEJANDRO J. KROLEWIECKI, PEDRO CORTADA, ROSANA FLORES, CESAR JAIME, LUIS ARIAS, CARLOS VILLALPANDO, ANAHÍ M. ALBERTI DÁMATO, JULIO R. NASSER ; JUAN P APARICIO

ACTA TROPICA

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2016 vol. 158 p. 24 - 31

0001-706X

After more than eighty years dengue reemerged in Argentina in 1997. Since then, the largestepidemic in terms of geographical extent, magnitude and mortality, was recorded in 2009. In thisreport we analyzed the DEN-1 epidemic spread in Orán, a mid-size city in a non-endemictropical area in Northern Argentina, and its correlation with demographic and socioeconomicfactors. Cases were diagnosed by ELISA between January and June 2009. We applied a space-time and spatial scan statistic under a Poisson model. Possible association between dengueincidence and socio-economic variables was studied with the Spearman correlation test. Theepidemic started from an imported case from Bolivia which generated two seminal clusters onFebruary, in the northeast and south parts of the city with risk ratios of 25.24 and 4.07respectively (p