INVESTIGADORES
MORENO Diego Martin
artículos
DALI, ANDREA; SEBASTIANI, FEDERICO; GABLER, THOMAS; FRATTINI, GIANFRANCO; MORENO, DIEGO M.; ESTRIN, DARÍO A.; BECUCCI, MAURIZIO; HOFBAUER, STEFAN; SMULEVICH, GIULIETTA
Proximal ligand tunes active site structure and reactivity in bacterial L. monocytogenes coproheme ferrochelatase
SPECTROCHIMICA ACTA. PART A, MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.; Año: 2024 vol. 313
ONO, DAISUKE; MOJICA, MARIA F.; BETHEL, CHRISTOPHER R.; ISHII, YOSHIKAZU; DRUSIN, SALVADOR I.; MORENO, DIEGO M.; VILA, ALEJANDRO J.; BONOMO, ROBERT A.
Structural role of K224 in taniborbactam inhibition of NDM-1
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Año: 2024 vol. 68
VILLAMIL, VALENTINA; ROSSI, MARIA-AGUSTINA; MOJICA, MARIA F.; HINCHLIFFE, PHILIP; MARTÍNEZ, VERÓNICA; CASTILLO, VALERIE; SAIZ, CECILIA; BANCHIO, CLAUDIA; MACÍAS, MARIO A.; SPENCER, JAMES; BONOMO, ROBERT A.; VILA, ALEJANDRO; MORENO, DIEGO M.; MAHLER, GRACIELA
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes
JOURNAL OF MEDICINAL CHEMISTRY; Lugar: Washington; Año: 2024
ALONSO, VICTORIA L.; ESCALANTE, ANDREA M.; RODRÍGUEZ ARAYA, ELVIO; FRATTINI, GIANFRANCO; TAVERNELLI, LUIS E.; MORENO, DIEGO M.; FURLAN, RICARDO L. E.; SERRA, ESTEBAN
1,3,4-oxadiazoles as inhibitors of the atypical member of the BET family bromodomain factor 3 from Trypanosoma cruzi (TcBDF3)
Frontiers in Microbiology; Año: 2024 vol. 15
ONO, DAISUKE; CMOLIK, ANNA; BETHEL, CHRISTOPHER R.; ISHII, YOSHIKAZU; DRUSIN, SALVADOR I.; MORENO, DIEGO M.; VILA, ALEJANDRO J.; BONOMO, ROBERT A.; MOJICA, MARIA F.
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2024 vol. 68
FABIO CORTÉS RODRÍGUEZ; FACUNDO DUALDE; PHILIPPE MASSIOT; GIANFRANCO FRATTINI; DIEGO M. MORENO; LUCIANO A. ABRIATA
Updates on moleculARweb, the Swiss Portal for Chemistry and Structural Biology Education Using Augmented and now also Virtual Reality
CHIMIA; Año: 2023 vol. 77 p. 264 - 265
CORDISCO, ESTEFANÍA; ZANOR, MARÍA INÉS; MORENO, DIEGO MARTÍN; SERRA, DIEGO OMAR
Selective inhibition of the amyloid matrix of Escherichia coli biofilms by a bifunctional microbial metabolite
npj Biofilms and Microbiomes; Año: 2023 vol. 9
DRUSIN, SALVADOR I.; LE TERRIER, CHRISTOPHE; POIREL, LAURENT; BONOMO, ROBERT A.; VILA, ALEJANDRO J.; MORENO, DIEGO M.
Structural basis of metallo-β-lactamase resistance to taniborbactam
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2023 vol. 68
RICHEZZI, MICAELA; FERREYRA, JOAQUÍN; PUZZOLO, JUAN; MILESI, LISANDRO; PALOPOLI, CLAUDIA M.; MORENO, DIEGO M.; HUREAU, CHRISTELLE; SIGNORELLA, SANDRA R.
Versatile Activity of a Copper(II) Complex Bearing a N4-Tetradentate Schiff Base Ligand with Reduced Oxygen Species
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY; Año: 2022
COLQUE, CLAUDIA A.; ALBARRACÍN ORIO, ANDREA G.; TOMATIS, PABLO E.; DOTTA, GINA; MORENO, DIEGO M.; HEDEMANN, LAURA G.; HICKMAN, RACHEL A.; SOMMER, LEA M.; FELIZIANI, SOFÍA; MOYANO, ALEJANDRO J.; BONOMO, ROBERT A.; K. JOHANSEN, HELLE; MOLIN, SØREN; VILA, ALEJANDRO J.; SMANIA, ANDREA M.
Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
mBio; Año: 2022
RODRÍGUEZ, FABIO CORTÉS; FRATTINI, GIANFRANCO; KRAPP, LUCIEN F.; MARTINEZ-HUNG, HASSAN; MORENO, DIEGO M.; ROLDÁN, MARIANA; SALOMÓN, JORGE; STEMKOSKI, LEE; TRAEGER, SYLVAIN; DAL PERARO, MATTEO; ABRIATA, LUCIANO A.
MoleculARweb: A Web Site for Chemistry and Structural Biology Education through Interactive Augmented Reality out of the Box in Commodity Devices
JOURNAL OF CHEMICAL EDUCATION; Lugar: Washington; Año: 2021
DÍAZ-STORANI, LUZ; CLARY, ANAELLE A.; MORENO, DIEGO M.; BALLARI, MARÍA SOL; PORTA, EXEQUIEL O.J.; BRACCA, ANDREA B.J.; JOHNSTON, JONATHAN B.; LABADIE, GUILLERMO R.
Synthesis and interaction of terminal unsaturated chemical probes with Mycobacterium tuberculosis CYP124A1
BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2021 vol. 44
HINCHLIFFE, PHILIP; MORENO, DIEGO M.; ROSSI, MARIA-AGUSTINA; MOJICA, MARIA F.; MARTINEZ, VERONICA; VILLAMIL, VALENTINA; SPELLBERG, BRAD; DRUSANO, GEORGE L.; BANCHIO, CLAUDIA; MAHLER, GRACIELA; BONOMO, ROBERT A.; VILA, ALEJANDRO J.; SPENCER, JAMES
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode
ACS Infectious Diseases; Año: 2021
ROSSI, MARIA-AGUSTINA; MARTINEZ, VERONICA; HINCHLIFFE, PHILIP; MOJICA, MARIA-FERNANDA; CASTILLO, VALERIE; MORENO, DIEGO MARTÍN; SMITH, RYAN; SPELLBERG, BRAD; DRUSANO, GEORGE L.; BANCHIO, CLAUDIA; BONOMO, ROBERT A.; SPENCER, JAMES; VILA, ALEJANDRO J.; MAHLER, GRACIELA
2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases
Chemical Science; Año: 2021
ROJAS, ARANTXA M. L.; DRUSIN, SALVADOR I.; CHOROSTECKI, UCIEL; MATEOS, JULIETA L.; MORO, BELÉN; BOLOGNA, NICOLAS G.; BRESSO, EDGARDO G.; SCHAPIRE, ARNALDO; RASIA, RODOLFO M.; MORENO, DIEGO M.; PALATNIK, JAVIER F.
Identification of key sequence features required for microRNA biogenesis in plants
NATURE COMMUNICATIONS; Año: 2020 vol. 11
OSELLA, M. I.; SALAZAR, M. O.; GAMARRA, M. D.; MORENO, D. M.; LAMBERTUCCI, F.; FRANCES, D. E.; FURLAN, R. L. E.
Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors
RSC Medicinal Chemistry; Año: 2020
ANA BORTOLOTTI; DANIELA BELÉN VAZQUEZ; JUAN CRUZ ALMADA; MARIA EUGENIA INDA; DRUSIN, SALVADOR I.; JUAN MANUEL VILLALBA; DIEGO M. MORENO; JEAN MARIE RUYSSCHAERT; LARISA ESTEFANIA CYBULSKI
A Transmembrane Histidine Kinase Functions as a pH Sensor
Biomolecules; Año: 2020 vol. 10
DRUSIN, SALVADOR I.; RASIA, RODOLFO M.; MORENO, DIEGO M.
Study of the role of Mg2+ in dsRNA processing mechanism by bacterial RNase III through QM/MM simulations
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY; Año: 2019
SOLÍS, VERÓNICA; PALOPOLI, CLAUDIA; DAIER, VERÓNICA; RIVIÈRE, ERIC; COLLIN, FABRICE; MORENO, DIEGO M.; HUREAU, CHRISTELLE; SIGNORELLA, SANDRA
Tuning the Mn II 2 /Mn III 2 redox cycle of a phenoxo-bridged diMn catalase mimic with terminal carboxylate donors
JOURNAL OF INORGANIC BIOCHEMISTRY; Año: 2018 vol. 182 p. 29 - 36
PUZZOLO, JUAN LUIS; DRUSIN, SALVADOR IVÁN; DAIER, VERÓNICA ANDREA; SIGNORELLA, SANDRA; MORENO, DIEGO MARTÍN
Using theoretical calculations to predict the redox potential of mononuclear manganese complexes
NEW JOURNAL OF CHEMISTRY; Año: 2018 vol. 42 p. 14827 - 14831
DEMICHELI, VERÓNICA; MORENO, DIEGO M.; RADI, RAFAEL
Human Mn-superoxide dismutase inactivation by peroxynitrite: a paradigm of metal-catalyzed tyrosine nitration in vitro and in vivo
METALLOMICS; Año: 2018 vol. 10 p. 679 - 695
GONZÁLEZ, LISANDRO J.; STIVAL, CINTIA; PUZZOLO, JUAN L.; MORENO, DIEGO M.; VILA, ALEJANDRO J.
Shaping Substrate Selectivity in a Broad-Spectrum Metallo-β-Lactamase
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Año: 2018 vol. 62
LISA, MARÍA-NATALIA; PALACIOS, ANTONELA R.; AITHA, MAHESH; GONZÁLEZ, MARIANO M.; MORENO, DIEGO M.; CROWDER, MICHAEL W.; BONOMO, ROBERT A.; SPENCER, JAMES; TIERNEY, DAVID L.; LLARRULL, LETICIA I.; VILA, ALEJANDRO J.
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases
NATURE COMMUNICATIONS; Año: 2017 vol. 8 p. 1 - 11
VERÓNICA A. DAIER; ERIC RIVIÈRE; SONIA MALLET-LADEIRA; DIEGO M. MORENO; CHRISTELLE HUREAU ; SANDRA R. SIGNORELLA
Synthesis, characterization and activity of imidazolate-bridged and Schiff-base dinuclear complexes as models of Cu,Zn-SOD. A comparative study
JOURNAL OF INORGANIC BIOCHEMISTRY; Lugar: Amsterdam; Año: 2016 vol. 163 p. 162 - 175
VERÓNICA DEMICHELI; DIEGO M. MORENO; GABRIEL E. JARA; ANALIA LIMA; SEBASTIAN CARBALLAL; NATALIA RIOS; CARLOS BATTHYANY; GERARDO FERRER-SUETA; CELIA QUIJANO; DARIO ESTRIN; MARCELO MARTI; RAFAEL RADI
Mechanism of the Reaction of human Mn-Superoxide Dismutase with Peroxynitrite: Nitration of Critical Tyrosine-34.
BIOCHEMISTRY; Lugar: Washington; Año: 2016 vol. 55 p. 3403 - 3417
JORGELINA MORÁN-BARRIO; MARÍA NATALIA LISA; NICOLE LARRIEUX; SALVADOR I. DRUSIN; ALEJANDRO M. VIALE; DIEGO M. MORENO; ALEJANDRO BUSCHIAZO; ALEJANDRO J. VILA
CRYSTAL STRUCTURE OF THE METALLO-BETA-LACTAMASE GOB IN THE PERIPLASMIC DI-ZINC FORM REVEALS AN UNUSUAL METAL SITE
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2016 vol. 60 p. 6013 - 6022
SALVADOR I. DRUSIN; IRINA P. SUAREZ; DIEGO F. GAUTO; RODOLFO M. RASIA; DIEGO M. MORENO
dsRNA-protein interactions studied by molecular dynamics techniques. Unravelling dsRNA recognition by DCL1
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Lugar: Amsterdam; Año: 2016 vol. 596 p. 118 - 125
LISANDRO J. GONZÁLEZ; DIEGO M. MORENO; ROBERT BONOMO; ALEJANDRO J. VILA
Host-Specific Enzyme-Substrate Interactions in SPM-1 Metallo-ß-Lactamase are Modulated by Second Sphere Residues.
PLOS PATHOGENS; Lugar: San Francisco; Año: 2014 vol. 10 p. 1 - 12
ALEJANDRA MARTINEZ; GONZALO PELUFFO; ARIEL A. PETRUK; MARTIN HUGO; DOLORES PINEYRO; VERÓNICA DEMICHELI; DIEGO M. MORENO; ANALIA LIMA; CARLOS BATTHYANY; ROSARIO DURÁN; CARLOS RUBELLO; MARCELO A. MARTI; NICOLE LARRIEUX; ALEJANDRO BUSCHIAZO; MADIA TRUJILLO; RAFAEL RADI; LUCIA PIACENZA
Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi Fe-superoxide dismutases A and B: Disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electro
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2014 vol. 289 p. 12760 - 12778
DEMICHELI, VERONICA; MORENO, DIEGO; JARA, GABRIEL E.; CARBALLAL, SEBASTIAN; QUIJANO, CELIA; FERRER-SUETA, GERARDO; RIOS, NATALIA; ESTRIN, DARIO; MARTI, MARCELO; RADI, RAFAEL
Mechanism of the Reaction of Peroxynitrite with Mn-Superoxide Dismutase: Nitration of Critical Tyrosine-34
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2014 vol. 76 p. 138 - 139
KATARZYNA RUDZKA; DIEGO M. MORENO; BETTY EIPPER; RICHARD MAINS; DARIO A. ESTRIN; L. MARIO AMZEL
Coordination of peroxide to the CuM center of peptidylglycine alpha-hydroxylating monooxygenase (PHM): structural and computational study
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY; Lugar: Berlin; Año: 2013 vol. 18 p. 223 - 232
DIEGO M. MORENO; MARCELO A. MARTÍ; PABLO M. DE BIASE; DARÍO A. ESTRIN; VERÓNICA DEMICHELI; RAFAEL RADI; LEONARDO BOECHI
Exploring the molecular basis of human manganese superoxide dismutase inactivation mediated by tyrosine 34 nitration
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Año: 2011 vol. 507 p. 304 - 309
PAU ARROYO-MAÑEZ; DAMIÁN E. BIKIEL; LEONARDO BOECHI; LUCIANA CAPECE; SANTIAGO DI LELLA; DARÍO A. ESTRIN; MARCELO A. MARTÍ; DIEGO M. MORENO; ALEJANDRO D. NADRA; ARIEL A. PETRUK
Protein dynamics and ligand migration interplay as studied by computer simulation
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS; Año: 2011 vol. 1814 p. 1054 - 1064
VERÓNICA DAIER; DIEGO MORENO; CARINE DUHAYON; JEAN-PIERRE TUCHAGUES; SANDRA SIGNORELLA
Synthesis, characterization and combined superoxide dismutase and catalase activities of manganese complexes of 1,4-bis(salicylidenamino)butan-2-ol
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY; Año: 2010 p. 965 - 974
DIEGO MORENO; VERONICA DAIER; CLAUDIA PALOPOLI,; JEAN-PIERRE TUCHAGUES; SANDRA SIGNORELLA,
Synthesis, characterization and antioxidant activity of water soluble MnIII complexes of sulphonato-substituted Schiff base ligands
JOURNAL OF INORGANIC BIOCHEMISTRY; Año: 2010 vol. 104 p. 496 - 502
MORENO DIEGO; PALOPOLI CLAUDIA; DAIER VERONICA; SHOVA SERGIU; VENDIER LAURE; GONZALEZ SIERRA MANUEL; TUCHAGUES JEAN-PIERRE; SIGNORELLA SANDRA
Synthesis, structure and catalase-like activity of dimanganese(III) complexes of 1,5-bis(X-salicylidenamino)pentan-3-ol (X = 3- and 5-methyl). Influence of phenyl-ring substituents on catalytic activity.
JOURNAL OF THE CHEMICAL SOCIETY, DALTON TRANSACTIONS; Lugar: Inglaterra; Año: 2006 vol. 2006 p. 5156 - 5166