INVESTIGADORES
GARRIZ Andres
congresos y reuniones científicas
Título:
New insights on the role of polyamines and polyaminooxidases in plant defense against pathogenic microorganisms
Autor/es:
MARÍA MARINA; MARÍA E. GONZALEZ; FR ROSSI; FERNANDO M. ROMERO; SANTIAGO J. MAIALE; GARRIZ A; BAUER ROLENE; OA RUIZ; FL PIECKENSTAIN
Lugar:
Ciudad del Cabo
Reunión:
Congreso; Structural Biology in the Bioeconomy; 2012
Resumen:
Polyamines, natural polycationic compounds essential for all living organisms, are involved in a variety of physiological processes. Polyamines are positively charged at physiological pH, thus interacting with negatively charged macromolecules such as nucleic acids and proteins. Plant polyamine metabolism is affected by a number of stresses, including pathogen infection. Recently, the use of model plants such as Nicotiana tabacum and Arabidopsis thaliana, as well as novel inhibitors of polyamine catabolism, increased our knowledge on the role of PAs in plant defense. Diamino and polyaminooxidases, which catabolize polyamines and release hydrogen peroxide, were shown to contribute to tobacco resistance to pathogenic bacteria, fungi and viruses. Modifications of plant spermine levels by different experimental approaches demonstrated that this tetraamine contributes to A. thaliana resistance to the biotrophic bacterium Pseudomonas viridiflava and cucumber mosaic virus. Interestingly, in planta spermine accumulation led to a variety of transcriptional changes related to plant defense. Further elucidation of PA-mediated changes in the expression of defense-related genes is a challenge for molecular plant pathologists.