INVESTIGADORES
PELLEGRINI Gretel Gisela
congresos y reuniones científicas
Título:
Evaluation of a new bovine biomaterial to induce mandibular bone healing in dental procedures.
Autor/es:
PELLEGRINI GG; GONZALES CHAVES MMS; DURAN F; ORZUZA R; ZENI SN
Reunión:
Congreso; SAIC; 2017
Institución organizadora:
SAIC
Resumen:
Bovine bone grafts are biocompatibile, osteoconductive, generate new bone apposition and prevent resorption. Synergy Bone Matrix (SBM) [Odontit Implant System, Argentina] effect was evaluated and compared with a recognized commercial material Bio-Oss (BO) [Geistlich, Switzerland] in rabbits. Bone healing process was evaluated by creating a critical sized bone defect (CSBD) at both sides of mandibles, and filling it with each biomaterial or remained unfilled (C: control). Assessments: clinical daily, systemic toxicity (usPCR and leukocytes) every 4 days, lungs, kidney and liver pathology, bone formation and device resorption evaluation; X-rays and compression and flexural biomechanical tests at sacrifice (4, 8 and 12 weeks). No systemic toxicity signs, fibrosis or adipose tissue development was observed. New bone formation, remaining bone substitute and mandibular radio-opacity were similar in BO and SBM. C presented significantly lower values (*p