SECCHIARI, FLORENCIA; NUÑEZ, SOL YANEL; SIERRA, JESSICA MARIEL; ZIBLAT, ANDREA; REGGE, MARÍA VICTORIA; RAFFO IRAOLAGOITIA, XIMENA LUCÍA; ROVEGNO, AGUSTÍN; AMERI, CARLOS; SECIN, FERNANDO PABLO; RICHARDS, NICOLÁS; RÍOS PITA, HERNANDO; VITAGLIANO, GONZALO; RICO, LUIS; MIEGGI, MAURO; FRASCHERI, FLORENCIA; BONANNO, NICOLÁS; BLAS, LEANDRO; TROTTA, ALDANA; FRIEDRICH, ADRIÁN DAVID; FUERTES, MERCEDES BEATRIZ; DOMAICA, CAROLINA INÉS; ZWIRNER, NORBERTO WALTER

The MICA-NKG2D axis in clear cell renal cell carcinoma bolsters MICA as target in immuno-oncology

OncoImmunology; Lugar: Londres; Año: 2022 vol. 11

SIERRA, JESSICA M.; SECCHIARI, FLORENCIA; NUÑEZ, SOL Y.; IRAOLAGOITIA, XIMENA L. RAFFO; ZIBLAT, ANDREA; FRIEDRICH, ADRIÁN D.; REGGE, MARÍA V.; SANTILLI, M. CECILIA; TORRES, NICOLÁS I.; GANTOV, MARIANA; TROTTA, ALDANA; AMERI, CARLOS; VITAGLIANO, GONZALO; PITA, HERNANDO RÍOS; RICO, LUIS; ROVEGNO, AGUSTÍN; RICHARDS, NICOLÁS; DOMAICA, CAROLINA I.; ZWIRNER, NORBERTO W.; FUERTES, MERCEDES B.

Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation

Frontiers in Immunology; Lugar: Lausanne; Año: 2021 vol. 12

ZWIRNER, NORBERTO W.; DOMAICA, CAROLINA I.; FUERTES, MERCEDES B.

Regulatory functions of NK cells during infections and cancer

JOURNAL OF LEUKOCYTE BIOLOGY; Año: 2021 vol. 109 p. 185 - 194

ZIBLAT, ANDREA; IRAOLAGOITIA, XIMENA LUCÍA RAFFO; NUÑEZ, SOL YANEL; TORRES, NICOLÁS IGNACIO; SECCHIARI, FLORENCIA; SIERRA, JESSICA MARIEL; SPALLANZANI, RAÚL GERMÁN; ROVEGNO, AGUSTÍN; SECIN, FERNANDO PABLO; FUERTES, MERCEDES BEATRIZ; DOMAICA, CAROLINA INÉS; ZWIRNER, NORBERTO WALTER

Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1

Frontiers in Immunology; Lugar: Lausanne; Año: 2021 vol. 12

FUERTES, MERCEDES BEATRIZ; DOMAICA, CAROLINA INÉS; ZWIRNER, NORBERTO WALTER

Leveraging NKG2D Ligands in Immuno-Oncology

Frontiers in Immunology; Lugar: Lausanne; Año: 2021 vol. 12

TORRES, NICOLÁS IGNACIO; REGGE, MARÍA VICTORIA; SECCHIARI, FLORENCIA; FRIEDRICH, ADRIÁN; SPALLANZANI, RAÚL GERMÁN; RAFFO IRAOLAGOITÍA, XIMENA LUCÍA; NÚÑEZ, SOL YANEL; SIERRA, JESSICA MARIEL; ZIBLAT, ANDREA; SANTILLI, MARÍA CECILIA; GILIO, NICOLÁS; ALMADA, EVANGELINA; LAUCHE, CONSTANZA; PARDO, ROMINA PAOLA; DOMAICA, CAROLINA INÉS; FUERTES, MERCEDES BEATRIZ; MADAUSS, KEVIN PATRICK; HANCE, KEN W.; GLOGER, ISRAEL; ZYLBERMAN, VANESA; GOLDBAUM, FERNANDO ALBERTO; ZWIRNER, NORBERTO WALTER

Restoration of anti-tumor immunity through anti-MICA antibodies elicited with a chimeric protein

Journal for ImmunoTherapy of Cancer; Lugar: Berlin; Año: 2020

NORBERTO WALTER ZWIRNER; MERCEDES BEATRIZ FUERTES; CAROLINA INES DOMAICA

LAS CÉLULAS LINFOIDES INNATAS. LOS NUEVOS ACTORES EN LA HOMEOSTASIS TISULAR Y LAS RESPUESTAS INFLAMATORIAS

MEDICINA (BUENOS AIRES); Año: 2019

ZIBLAT, ANDREA; NUÑEZ, SOL Y.; RAFFO IRAOLAGOITIA, XIMENA LUCÍA; SPALLANZANI, RAÚL GERMAN; TORRES, NICOLÁS I.; SIERRA, JESSICA M.; SECCHIARI, FLORENCIA; DOMAICA, CAROLINA I.; FUERTES, MERCEDES B.; ZWIRNER, NORBERTO W.

Interleukin (IL)-23 Stimulates IFN-γ Secretion by CD56bright Natural Killer Cells and Enhances IL-18-Driven Dendritic Cells Activation

Frontiers in Immunology; Lugar: Bethesda; Año: 2018 vol. 8

SOL YANEL NUÑEZ; ANDREA ZIBLAT; FLORENCIA SECCHIARI; NICOLAS I. TORRES; JESSICA MARIEL SIERRA; XIMENA LUCIA RAFFO; ROMINA ELIZABETH ARAYA; CAROLINA INES DOMAICA; MERCEDES BEATRIZ FUERTES; NORBERTO WALTER ZWIRNER

M2 macrophages limit NK cell-mediated cytotoxicity and IFN-gamma; secretion through different mechanisms

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2018

XIMENA LUCIA RAFFO; RAUL GERMAN SPALLANZANI; NICOLAS I. TORRES; ROMINA ELIZABETH ARAYA; ANDREA ZIBLAT; CAROLINA INES DOMAICA; JESSICA MARIEL SIERRA; SOL YANEL NUÑEZ; FLORENCIA SECCHIARI; THOMAS GAJEWSKI; NORBERTO WALTER ZWIRNER; MERCEDES BEATRIZ FUERTES

NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2016 vol. 197

ANDREA ZIBLAT; CAROLINA I. DOMAICA; RAUL GERMAN SPALLANZANI; XIMENA LUCIA RAFFO; LUCAS EZEQUIEL ROSSI; DAMIAN EZEQUIEL AVILA; NICOLAS I. TORRES; MERCEDES BEATRIZ FUERTES; NORBERTO W. ZWIRNER

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

EUROPEAN JOURNAL OF IMMUNOLOGY; Lugar: Weinheim; Año: 2015 vol. 45 p. 192 - 202

RAUL GERMAN SPALLANZANI; NICOLAS I. TORRES; DAMIAN EZEQUIEL AVILA; ANDREA ZIBLAT; XIMENA LUCIA RAFFO; LUCAS EZEQUIEL ROSSI; CAROLINA I. DOMAICA; MERCEDES BEATRIZ FUERTES; GABRIEL A. RABINOVICH; NORBERTO W. ZWIRNER

Regulatory Dendritic Cells Restrain NK Cell IFN-g Production through Mechanisms Involving NKp46, IL-10, and MHC Class I?Specific Inhibitory Receptors

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2015 vol. 195

RAUL GERMAN SPALLANZANI; TOMAS DALOTTO; XIMENA LUCIA RAFFO; ANDREA ZIBLAT; CAROLINA INES DOMAICA; DAMIAN EZEQUIEL AVILA; LUCAS EZEQUIEL ROSSI; MERCEDES BEATRIZ FUERTES; MARIA AGUSTINA BATTISTONE; GABRIEL ADRIAN RABINOVICH; MARIANA SALATINO; NORBERTO WALTER ZWIRNER

Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions

CANCER IMMUNOLOGY IMMUNOTHERAPY; Lugar: Berlin; Año: 2013 vol. 62 p. 1781 - 1795

DIEGO O. CROCI; MARIANA SALATINO; NATALIA RUBINSTEIN; JUAN P. CERLIANI; LUCAS E CAVALLIN; HOWARD J. LEUNG; JING OUYANG; JUAN M. ILARREGUI; MARTA A.TOSCANO; CAROLINA I. DOMAICA; MARÍA C. CROCI; MARGARET A. SHIPP; ENRIQUE A. MESRI; ADRIANA ALBINI; GABRIEL A. RABINOVICH

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma.

JOURNAL OF EXPERIMENTAL MEDICINE; Lugar: New York; Año: 2012 p. 1985 - 2000

CAROLINA INES DOMAICA; MERCEDES BEATRIZ FUERTES; IGNACIO URIARTE; MARÍA VICTORIA GIRART; JESSICA SARDANOUS; DORINA ILEANA COMAS; DANIELA DI GIOVANNI; MARÍA ISABEL GAILLARD; LILIANA BEZRODNIK; NORBERTO W. ZWIRNER

Human Natural Killer cell maturation defect supports in vivo CD56bright to CD56dim lineage development

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 51677 - 51689

LUCAS EZEQUIEL ROSSI; DAMIAN EZEQUIEL AVILA; RAUL GERMAN SPALLANZANI; ANDREA ZIBLAT; MERCEDES BEATRIZ FUERTES; LARA LAPYCKYJ; DIEGO O. CROCI; GABRIEL ADRIAN RABINOVICH; CAROLINA INES DOMAICA; NORBERTO WALTER ZWIRNER

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression

JOURNAL OF LEUKOCYTE BIOLOGY; Lugar: Bethesda; Año: 2011 p. 321 - 331

NORBERTO W. ZWIRNER; DIEGO O. CROCI; CAROLINA I. DOMAICA; GABRIEL A. RABINOVICH

Overcoming the Hurdles of Tumor Immunity by Targeting Regulatory Pathways in Innate and Adaptive Immune Cells

CURRENT PHARMACEUTICAL DESIGN.; Lugar: Oak Park, IL; Año: 2010 vol. 16 p. 255 - 267

NORBERTO W. ZWIRNER; CAROLINA I. DOMAICA

Cytokine regulation of natural killer cell effector functions

BIOFACTORS; Lugar: Malden, MA; Año: 2010 vol. 36 p. 274 - 288

DOMAICA CI; FUERTES MB; ROSSI LE; GIRART MV; AVILA DE; RABINOVICH GA; ZWIRNER NW

Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands.

EMBO REPORTS; Lugar: Londres; Año: 2009 vol. 10 p. 908 - 915

FUERTES MB; GIRART MV; MOLINERO LL; DOMAICA CI; ROSSI LE; BARRIO MM; MORDOH J; RABINOVICH GA; ZWIRNER NW

Intracellular retention of the NKG2D ligand MHC Class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity.

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2008 vol. 180 p. 4606 - 4614

MARÍA VICTORIA GIRART; MERCEDES BEATRIZ FUERTES; CAROLINA INES DOMAICA; LUCAS EZEQUIEL ROSSI; NORBERTO WALTER ZWIRNER

Engagement of TL3, TLR7 and NKG2D regulates IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2007 vol. 179 p. 3472 - 3479

NORBERTO WALTER ZWIRNER; MERCEDES BEATRIZ FUERTES; MARÍA VICTORIA GIRART; CAROLINA INES DOMAICA; LUCAS EZEQUIEL ROSSI

Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system.

CYTOKINE & GROWTH FACTOR REVIEWS; Lugar: Nueva York; Año: 2007 vol. 18 p. 159 - 170

CAROLINA INES DOMAICA; LUCIANA LORENA MOLINERO; MERCEDES BEATRIZ FUERTES; MARÍA VICTORIA GIRART; LUCAS EZEQUIEL ROSSI; NORBERTO WALTER ZWIRNER

Intracellular expression of MICA in activated CD4 T lymphocytes and protection from NK cell-mediated MICA-dependent cytotoxicity.

HUMAN IMMUNOLOGY; Lugar: New York; Año: 2006 vol. 67 p. 170 - 182

NORBERTO WALTER ZWIRNER; MERCEDES BEATRIZ FUERTES; MARÍA VICTORIA GIRART; CAROLINA INES DOMAICA; LUCAS EZEQUIEL ROSSI

Immunobiology of the human MHC class I chain-related gene A (MICA): from tansplantation immunology to tumor immune escape.

Inmunologia; Lugar: Barcelona; Año: 2006 vol. 25 p. 25 - 38