Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina

GARCÍA MARTÍ, S.; AUGUSTOVSKI, F.; PICHÓN RIVIERE, A.

EPIDEMIOLOGY AND INFECTION.

CAMBRIDGE UNIV PRESS

Año: 2019 vol. 147

0950-2688

Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20-25% and a reduction in AGE-related hospitalisations of 55-60%. The vaccine impact was similar for each age group considered (