Evaluation of analgesic, sympathetic and motor effects of 1% and 2% lidocaine administered epidurally in dogs undergoing ovariohysterectomy

CLAUSSE, MARÍA; GUTIERREZ, VERÓNICA; MARTIN-FLORES, MANUEL; CLAUSSE, MARÍA; GUTIERREZ, VERÓNICA; MARTIN-FLORES, MANUEL; LANDIVAR, FLORENCIA; CAVILLA, VERÓNICA; DEL SOLE, MARÍA; LANDIVAR, FLORENCIA; CAVILLA, VERÓNICA; DEL SOLE, MARÍA; NEJAMKIN, PABLO; LORENZUTTI, MATÍAS; VIVIANI, PAULA; NEJAMKIN, PABLO; LORENZUTTI, MATÍAS; VIVIANI, PAULA

VETERINARY ANAESTHESIA AND ANALGESIA

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2020 vol. 47 p. 797 - 802

1467-2987

Objective: To compare, versus a control, the sensory, sympathetic and motor blockade of lidocaine 1% and 2% administered epidurally in bitches undergoing ovariohysterectomy. Study design: Randomized, blinded, controlled clinical trial. Animals: A total of 24 mixed-breed intact female dogs. Methods: All dogs were administered dexmedetomidine, tramadol and meloxicam prior to general anesthesia with midazolam?propofol and isoflurane. Animals were randomly assigned for an epidural injection of lidocaine 1% (0.4 mL kg−1; group L1), lidocaine 2% (0.4 mL kg−1; group L2) or no injection (group CONTROL). Heart rate (HR), respiratory rate (fR), end-tidal partial pressure of carbon dioxide (PE′CO2), and invasive systolic (SAP), mean (MAP) and diastolic (DAP) arterial pressures were recorded every 5 minutes. Increases in physiological variables were treated with fentanyl (3 μg kg−1) intravenously (IV). Phenylephrine (1 μg kg−1) was administered IV when MAP was