RELATION BETWEEN GENDER, PSYCHIATRIC AND COGNITIVE DISORDERS AND EXPERIENTIAL AURAS IN PATIENTS WITH TEMPORAL LOBE EPILEPSY

BENJUMEA CUARTAS, V; GIAGANTE, B; ODDO, S; PEREIRA DE SILVA, N; D' ALESSIO, L; FERNÁNDEZ LIMA, M; SOLÍS, P; PRINCICH, J; SEOANE, P; SEOANE, E; KOCHEN, S.

Barcelona

Congreso; 2° International Epilepsy Congress; 2017

International league against epilepsy (ILAE) y la International Bureau for epilepsy (IBE)

Purpose: To determine whether the experiential auras in patients with temporal lobe epilepsy (TLE) are related to gender, educational level, psychiatric comorbidity, visual or verbal material-specific memory impairment, lateralization by video-EEG and epileptogenic lesions on brain MRI.Method: Retrospective review (1998 ? 2015) of clinical charts and video-EEG of patients with experiential auras and TLE followed at the JM Ramos Mejía and El Cruce Hospitals.Results: We included 35 patients, 51.4% were male, mean age 35 years, mean epilepsy duration 20.3 years. Laterality of the epileptogenic zone was right (57.1%) and left (37.1%) temporal. An epileptogenic lesion was detected in most of cases and hippocampal sclerosis was the most common finding. Seventy-four percent of patients underwent epilepsy surgery (Engel I-II: 65.4%). Educational level was mainly primary and secondary. Most of patients presented visual or both memories deficits associated with executive dysfunction. Almost half patients had a psychiatric comorbidity. Deja vu was the most frequent experiential aura (60%), followed by Jamais vu (20%), strangeness (20%) and depersonalization (14.3%). Most patients had a single experiential aura (Deja vu 54.5%, Jamais vu 18.2%, strangeness 13.6%, depersonalization 9.1%, prescience 4.5%) associated with non-experiential auras in the majority of cases. Conclusion: Most of patients presented a single experiential aura, most frequently Deja vu, associated with non-experiential auras, mainly fear. A right temporal lobe seizure focus was the most frequent. In terms of gender, Deja vu was more common in male patients. A high prevalence of psychiatric comorbidity was observed and despite of the reduced number of cases, the 3 patients with psychosis presented Deja vu. Most of patients presented visual or both memories deficits associated with executive dysfunction. We did not find any relation between the experiential auras and educational level.