Artificial Pancreas: First Clinical Trials in Argentina

LUIS GROSEMBACHER; RICARDO S. SÁNCHEZ PEÑA; PATRICIO COLMEGNA

Toulouse

Congreso; IFAC World Congress; 2017

International Federation of Automatic Control (IFAC)

The first clinical trials using an Articial Pancreas (AP) in Latin America have beendened in 2 stages. The first stage was carried out in November 2016 with the UVA controller(developed by the Center for Diabetes Technology and already clinically tested), and the second will be performed during the first semester of 2017 with the ARG (Automatic Regulation of Glucose) algorithm (developed by ITBA, UNQ, and UNLP in Argentina). Both tests are based on the DiAs (Diabetes Assistant) from the UVA, and are performed in the HIBA on 5 patients with Type 1 Diabetes Mellitus (T1DM), for 36 hours. For the rst stage, Open-Loop (OL) insulin boluses were applied before meals and patient´s physical activity was included. On the other hand, for the second stage, patients will not be involved in physical activity, but no OL insulin boluses will be injected before meals. In this work, experimental results from the first stage with the UVA controller, and preliminary results with the ARG control algorithm tested on the UVA/Padova simulator are presented. Due to the nal paper deadline, the experimental results from the second stage are not included here, but will be presented at the IFAC World Congress.