MODERATE RUNNING PROTECTS AGAINST PANCREAS DAMAGE IN CHRONIC COLA DRINKING RATS

OTERO-LOSADA, MATILDE; J GONZALES; MULLER ANGÉLICA DEL CARMEN; G OTTAVIANO; G CAO; AMBROSIO G; J MILEI

París

Congreso; 26 th European Society of Hypertension and Protection; 2016

European Meeting Society

MODERATE RUNNING PROTECTS AGAINST PANCREAS DAMAGE IN CHRONIC COLA DRINKING RATSAutor/es:OTERO-LOSADA M.; GONZALEZ J; MULLER A; OTTAVIANO G; CAO G; AMBROSIO G.; MILEI J.Lugar:ParisReunión:Congreso; European Society of Hypertension ESH 2016 ANNUAL MEETING; 2016Institución organizadora:European Society of HypertensionResumen:This study evaluates whether the daily practice of an exercise routine might protect from endocrine pancreas damage in cola drinking rats.Forty-eight Wistar rats were randomly assigned to 4 groups depending on a) beverage consumption ad libitum, water (W) or cola beverage (C), and b) physical activity, sedentary (S) or treadmill running (R). Accordingly, 4 groups were studied: WS (water. sedentary), WR (water runner). CS (cola sedentary) and CR (cola runner).Body weight, nutritional data, plasma levels of glucose, creatinine, total cholesterol and cholesterol fractions, and triglycerides (enzymocolorimetry), and systolic blood pressure (plethysmography) were measured.After 6 months, euthanasia was performed (overdose sodium thiopental). Pancreatic tissue was immediately excised and conventionally processed for morphometrical and immunohistochemical determinations.The effects of running and chronic cola drinking on pancreas morphology showed interaction (p