IFIBIO HOUSSAY   25014
INSTITUTO DE FISIOLOGIA Y BIOFISICA BERNARDO HOUSSAY
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
HVC neural activity supports a circular model for birdsong production
Autor/es:
CECILIA HERBERT; GABRIEL B. MINDLIN; SANTIAGO BOARI; ANA AMADOR; MARIANO BELLUSCIO
Lugar:
Mar del Plata
Reunión:
Congreso; XXXII Congress of the Argentine Society for Research in Neuroscience; 2017
Institución organizadora:
Argentine Society for Research in Neuroscience
Resumen:
p { margin-bottom: 0.1in; line-height: 120%; }Songbirdsare a well-established animal model for the study of vocalproduction, perception and learning. During singing, the respiratorysystem and the vocal organ are driven by neural instructions from aset of nuclei dedicated to song production. Telencephalic nucleus HVC(used as a proper name) plays a key role in the production of motorcommands that drive the periphery. In canaries (Serinus canaria), theinteraction between air sac pressure and muscle tension necessary forsong production has been previously studied in detail. Recently,these biomechanical motor gestures have been obtained as solutions toa neural population model of the song system. This model makesspecific predictions about the timing of the sparse activity in theneural nucleus HVC during the production of motor gestures. Wedeveloped a tetrode array to chronically record extracellularactivity in HVC of singing canaries. We were able to isolate singleunits from the recorded data and found a set of neurons locked tosinging behavior for different phrases. We analyzed spike time delaywith respect to syllable onset for specific phrases and found thatneurons fire at a particular instance within a syllable and robustlyfor all syllables within a phrase across renditions. Spike times fromdifferent syllables from two birds occur at note transitions withinthe syllable. These findings support the predictions from the neuralpopulation model.