Effects of Photobiomodulation Therapy on Oxidative Stress in Muscle Injury Animal Models: A Systematic Review

SERRA, ANDREY JORGE; DOS SANTOS VIEIRA, MARCIA ATAÍZE; VASCONSUELO, ANDREA; STANCKER, TATIANE GARCIA; DOS SANTOS, SOLANGE ALMEIDA; LEAL-JUNIOR, ERNESTO CESAR; SIMÕES, MAÍRA CECÍLIA BRANDÃO; SANTOS, SIMONE SILVA; PROKIC, MARKO; DE CARVALHO, PAULO DE TARSO CAMILLO

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY

LANDES BIOSCIENCE

Año: 2017 vol. 2017 p. 1 - 8

1942-0900

This systematic review was performed to identify the role of photobiomodulation therapy on experimental muscle injury modelslinked to induce oxidative stress. EMBASE, PubMed, and CINAHL were searched for studies published from January 2006 toJanuary 2016 in the areas of laser and oxidative stress. Any animal model using photobiomodulation therapy to modulateoxidative stress was included in analysis. Eight studies were selected from 68 original articles targeted on laser irradiation andoxidative stress. Articles were critically assessed by two independent raters with a structured tool for rating the research quality.Although the small number of studies limits conclusions, the current literature indicates that photobiomodulation therapy canbe an effective short-term approach to reduce oxidative stress markers (e.g., thiobarbituric acid-reactive) and to increaseantioxidant substances (e.g., catalase, glutathione peroxidase, and superoxide dismutase). However, there is a nonuniformity inthe terminology used to describe the parameters and dose for low-level laser treatment.